Understanding the Risks of Potential C. Difficile Recurrence
A 32-year-old male, measuring 180 cm and weighing 65 kg, has faced a serious bout with C. difficile, necessitating hospitalization and treatment with vancomycin five weeks ago (PCR positive, toxin negative). Recent tests revealed that his calprotectin levels significantly decreased from 1800 to 25 last week. Today, he is starting to experience symptoms reminiscent of his previous episode, including elevated heart rate (over 110 bpm), feelings of dizziness, a fever of 38.5°C, reduced appetite, and audible bowel sounds. However, he has not yet experienced loose stools or green vomit as he did during the earlier illness, with those symptoms emerging just a day after the onset.
The doctor could only accommodate him for a consultation a month later. He is wondering if it would be wise to seek urgent care if his symptoms do not worsen or if it is still crucial to consult a physician despite the current mildness of his symptoms. Fortunately, he is managing to keep fluids down and has been able to consume small portions of food, which raises hopes that he may not be facing another infection of C. difficile.
Additional context from the past year includes abdominal pain appearing two hours post-meal, a 10 kg weight loss, and challenges with swallowing pills and food, for which he is awaiting an ENT appointment. An X-ray indicated that food was becoming lodged in the pyriform sinus, and he has been experiencing nighttime balance issues. Treatments with PPIs and famotidine have not yielded improvement, and a colonoscopy performed two weeks ago showed no abnormalities. Furthermore, he had his gallbladder removed nine years ago, and his bilirubin levels have consistently been above 40 µmol/L.
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