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Understanding Multilevel Thoracic Spondylosis in the Context of Familial Rheumatoid Arthritis

I’m a 50-year-old female, measuring 5’4” and weighing 212 pounds. Currently, I am undergoing treatment with Lamotrigine and Ketamine infusions for treatment-resistant depression and PTSD. Additionally, I take Wegovy tablets for weight management. Recently, I sought the expertise of a rheumatologist due to a six-month period of increasingly severe joint pain throughout my body and corresponding stiffness. This change coincides with a significant family history of severe seronegative rheumatoid arthritis; my family includes a brother, mother, and three out of four grandparents who have battled this condition. Notably, two of these relatives have also been diagnosed with ankylosing spondylitis. It appears I was not fortunate in the genetic department. To further investigate my symptoms, my doctor recommended various tests, including blood work, X-rays, and two MRIs. The results indicated mild to moderate degenerative joint disease (DJD). The radiologist's report revealed the following details: I have a follow-up appointment scheduled with the rheumatologist in a month. While I maintain a sense of calm about the situation, I would deeply appreciate any insights from medical professionals to help clarify the findings outlined below. I prefer not to rely on platforms like ChatGPT or internet searches for health-related queries, as they often lead to unnecessary alarm. Results are summarized as follows: **MRI of the thoracic spine without contrast** - At T4-T5, T5-T6, and T6-T7 levels, there is a mild disc bulge accompanied by a small 2 mm left paracentral disc protrusion, which is resulting in mild stenosis of the left foraminal space. No issues with canal or right foraminal stenosis were detected. It’s possible that the left paracentral disc protrusion might be in contact with the spinal cord without altering signal. - There is evidence of mild multilevel thoracic spondylosis. **Bilateral hip X-ray** - The X-ray indicates mild DJD in both hips. - There is visibility of bilateral acetabular protrusion, potentially leading to impingement; further clinical correlation is warranted. Thank you immensely for your consideration and any assistance you can offer.

AsthmaAllergy & ImmunologyDermatology
Male25-34
6 minutes ago

Exploring Alternative Options for Managing Large Fibroadenomas Without Surgery

I am a 27-year-old woman managing several health conditions. Currently, I am prescribed 20mg of fluoxetine to help with OCD and intense premenstrual syndrome. Additionally, I take spironolactone for hormonal acne and seborrheic dermatitis. I have a history of lupus, which is nearing remission, and I'm not on any medication for it at this time. My concern lies with the presence of multiple significant fibroadenomas in both of my breasts. We stopped counting them after numerous ultrasounds, as it became clear there were too many to identify. I had biopsies taken from ten distinct masses, five on each side, all of which were confirmed as complex benign fibroadenomas. It's not uncommon for some individuals to develop many of these, but mine are notably large. Their size causes me substantial pain, impacting my sleep, gym activities, and even my ability to breathe comfortably. Many of these masses range from 3 to 8 centimeters. I've undergone surgical removal for several of these large and painful fibroadenomas. However, I was cautioned that they might return to their previous size, and unfortunately, that seems to be happening. I cannot continually opt for surgery every few months to address this issue. Despite my discussions with my surgeon and primary care physician, they haven't presented alternative solutions beyond surgery. I am feeling quite overwhelmed and anxious about this situation. While I am relieved they are not cancerous, their presence is significantly affecting my quality of life. Are there any other treatment options available? I am eager for any information or advice that could help me manage this condition more effectively.

ArthritisLupusFibromyalgia
Male25-34
6 minutes ago

Understanding the Risks of Potential C. Difficile Recurrence

A 32-year-old male, measuring 180 cm and weighing 65 kg, has faced a serious bout with C. difficile, necessitating hospitalization and treatment with vancomycin five weeks ago (PCR positive, toxin negative). Recent tests revealed that his calprotectin levels significantly decreased from 1800 to 25 last week. Today, he is starting to experience symptoms reminiscent of his previous episode, including elevated heart rate (over 110 bpm), feelings of dizziness, a fever of 38.5°C, reduced appetite, and audible bowel sounds. However, he has not yet experienced loose stools or green vomit as he did during the earlier illness, with those symptoms emerging just a day after the onset. The doctor could only accommodate him for a consultation a month later. He is wondering if it would be wise to seek urgent care if his symptoms do not worsen or if it is still crucial to consult a physician despite the current mildness of his symptoms. Fortunately, he is managing to keep fluids down and has been able to consume small portions of food, which raises hopes that he may not be facing another infection of C. difficile. Additional context from the past year includes abdominal pain appearing two hours post-meal, a 10 kg weight loss, and challenges with swallowing pills and food, for which he is awaiting an ENT appointment. An X-ray indicated that food was becoming lodged in the pyriform sinus, and he has been experiencing nighttime balance issues. Treatments with PPIs and famotidine have not yielded improvement, and a colonoscopy performed two weeks ago showed no abnormalities. Furthermore, he had his gallbladder removed nine years ago, and his bilirubin levels have consistently been above 40 µmol/L. Thank you for taking the time to read this.

LupusCrohn's DiseaseInternal Medicine
Male25-34
26 minutes ago