Is it Safe to Use CBD While on Celecoxib?
Hello everyone! I'm a 28-year-old male, standing 6 feet tall, and I don’t smoke tobacco. At the moment, I’m on a daily regimen of celecoxib, taking 200mg each day. I’ve been curious about the safety of using CBD-rich cannabis alongside my celecoxib treatment. I typically consume CBD during the intervals when I’m not taking celecoxib. I’ve noticed that the effects of CBD differ from those of celecoxib in managing the inflammation associated with my autoimmune condition, and it also helps me manage my stress levels better. I would greatly appreciate any insights or advice on this matter!
Answers (1)
2/17/2026, 1:40:32 AM
OpenHealth AI
Using CBD while on celecoxib is a topic that requires careful consideration, as interactions between medications can impact your health. First, it's great to see you're being proactive about your treatment and looking for ways to manage your condition.
Summary of Main Points:
- While there's limited research on the interaction between CBD and celecoxib, caution is advised.
- Both substances have anti-inflammatory properties, but they may affect liver enzymes differently.
- Monitoring how you feel and any symptoms is crucial.
Explanation:
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce inflammation and pain, especially in autoimmune conditions. CBD (cannabidiol) is often used for its potential therapeutic effects, including reducing anxiety and inflammation.
However, CBD can interact with liver enzymes (particularly the CYP450 system), which are involved in metabolizing many medications, including celecoxib. This means that while CBD may not directly interfere with celecoxib, it could alter how your body processes this medication, potentially increasing the risk of side effects or reducing efficacy.
Next Steps:
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Continue Tracking Effects: Since you notice different effects from CBD, keep a journal of your symptoms and any changes you observe during your CBD use, especially in relation to celecoxib.
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Time Your Dosages: Since you consume CBD when not taking celecoxib, monitor whether taking them at different times helps reduce any potential interactions.
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Watch for Side Effects: Be alert for any unusual symptoms, such as increased bruising, gastrointestinal problems, or changes in liver function (like yellowing of the skin/eyes).
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Stay Educated: Research ongoing studies or credible sources regarding CBD's interactions with NSAIDs and consider any new guidelines that might emerge.
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Consult a Healthcare Provider: While I’m not suggesting an immediate consultation, keeping your doctor updated about your CBD use can help assure safety and tailor your treatment plan effectively.
Feel free to share more about your experiences or concerns; I’m here to help!
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