Seeking Guidance on Medication Interactions for Depression, ADHD, and Weight Management
I’m currently located in the UK and dealing with a somewhat fragmented healthcare situation. I’m reaching out for advice regarding my health conditions and medication management, if anyone has insights to offer. At the age of 31, I stand at 165 cm and weigh 175 lbs. My journey with clinical depression and generalized anxiety disorder began during my teenage years, and over the last decade, I have seen my weight steadily rise, with some minor fluctuations along the way. Here’s a breakdown of my current medications: - 20mg of Prozac (I was previously on 100mg of Sertraline/Zoloft) - Microgynon 30 combined pill, taken back-to-back without breaks - Topical treatments including Differin and Finacea Additionally, I’m taking the following supplements: - Iron tablets (I was informed I’m borderline anemic during my last blood tests) - Vitamin D - 1200mg of NAC for excoriation disorder - Biotin - Vitamin B12 Recently, I received a diagnosis of inattentive ADHD through the NHS Right to Choose pathway. I’m now waiting for a follow-up appointment regarding ADHD medication options, but I’m aware that some of these might interact with Prozac, which is a concern for me. Given that I’m currently experiencing a depressive episode, my weight issue is becoming increasingly problematic, affecting my mobility due to congenital bilateral hip dysplasia, which I had treated in childhood but remains unresolved. I would like to know if it would be advisable, considering my existing medications and the possibility of future ADHD treatments, to begin using Ozempic or Wegovy to help manage my weight. I had previously used Mounjaro with great success, but I made the error of stopping it suddenly and failed to maintain the necessary lifestyle changes. Unfortunately, Mounjaro has become prohibitively expensive in the UK, leading me to explore Ozempic/Wegovy as alternatives. Are there any potential adverse interactions or important considerations I should be aware of with the combination of Prozac, Ozempic, and standard ADHD medications, along with my daily supplements? I appreciate any further questions for clarification—thank you in advance for your support!
Answers (1)
2/4/2026, 11:00:59 PM
OpenHealth AI
It's great that you're taking the time to research your health situation and explore your medication options. Managing depression, ADHD, and weight can be complex, especially with your current medications. Let’s break this down:
Key Points:
- Current Medications: Prozac (Fluoxetine) for depression; Microgynon for birth control; topical treatments for skin; iron and vitamins as supplements.
- Concerns: Managing interactions between Prozac, potential ADHD medications, and weight management options like Ozempic or Wegovy.
- Health Context: Inattentive ADHD diagnosis, weight management challenges impacting mobility due to existing hip dysplasia.
Explanation:
Each medication you’re on has specific actions, and it's wise to be cautious about interactions. Prozac (Fluoxetine) is a selective serotonin reuptake inhibitor (SSRI) used for depression and anxiety. Ozempic (semaglutide) and Wegovy are medications primarily used for weight management; they are GLP-1 receptor agonists.
- ADHD Medications: Common ADHD medications (such as stimulants) can sometimes impact mood, and SSRIs like Prozac can be prescribed together with them. However, some medications may have a higher risk of interactions, particularly regarding mood stabilization.
- Ozempic/Wegovy and Prozac: Current evidence suggests that these weight management medications do not have significant direct interactions with Prozac. However, the effects on your mental health should be monitored, as any medication change can have psychological impacts.
Next Steps:
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Consult Your Prescriber: It's vital to discuss potential ADHD medications with your healthcare provider, including how they might interact with Prozac. Ask specifically about any recommended treatments and their implications for your mental health and weight management.
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Consider Starting Ozempic/Wegovy: Given your previous positive response to Mounjaro and the unbearable cost of continuing it, discuss with your healthcare provider the option of starting Ozempic or Wegovy, keeping in mind your mental health status.
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Lifestyle Changes: Engage in dietary adjustments and physical activities that suit your mobility needs, which can complement any medication adjustments for weight loss. Small changes can be impactful over time.
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Monitor Your Health: Keep a detailed record of how you feel physically and mentally as you potentially introduce new medications or change existing ones. This record can inform discussions with your healthcare provider during follow-ups.
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Support Networks: Seek support or groups for mental health and weight management if you feel that would help. Engaging with others can provide shared experiences and support.
You're taking an important step by seeking information and preparing for discussions with your healthcare provider. Stay proactive about your health, and don’t hesitate to ask questions along the way. Let me know if you have more concerns or require additional information!
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