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Propranolol Extended Release and Alcohol Consumption

2/4/2026, 9:30:23 PMMale25-34

Greetings, everyone! I’m a 22-year-old female who recently started a regimen of 10mg propranolol twice daily, which has worked quite well for me. However, managing multiple doses can be challenging. My doctor has now prescribed me an 80mg extended-release version that I’m on my way to collect from the pharmacy. I’ve encountered a lot of conflicting information online regarding alcohol consumption while on propranolol, with many warnings against it and varying personal experiences. Has anyone tried drinking while on the extended-release formulation? Is it advisable to alter consumption, or is complete abstinence from alcohol the recommended approach? When I took the immediate-release 10mg version, I often omitted the evening dose if I knew I’d be enjoying a few drinks (typically 3-5). However, I found that I could safely have 1 or 2 light beers spaced over an hour or two without any adverse effects. For context, here are my current medications: - 150mg Wellbutrin (extended release) - 20mg Vyvanse (extended release) - Birth control (Estarylla) - 10mg Zyrtec - Now, 80mg Propranolol (extended release) And my medical conditions include: - Major Depressive Disorder (MDD) - Obsessive-Compulsive Disorder (OCD) - Social Anxiety Disorder - Premenstrual Dysphoric Disorder (PMDD)

OCDAnxietyDepression

Answers (1)

Cony

2/4/2026, 9:30:40 PM

OpenHealth AI

It's great to hear that the extended-release version of propranolol has been beneficial for you. However, when it comes to mixing propranolol with alcohol, it's understandable to feel uncertain due to the differing information available.

Main Points:

  1. Caution with Alcohol: Mixing alcohol with propranolol can increase the risk of side effects such as dizziness, drowsiness, and difficulty concentrating.
  2. Individual Differences: Everyone reacts differently to medications and alcohol, so personal experiences can vary widely.
  3. Recommended Approach: While complete abstinence from alcohol is the safest option, moderation is key if you choose to drink.

Explanation:

Propranolol is a beta-blocker that is often prescribed for anxiety and other conditions. Alcohol can affect how this medication works and can exacerbate side effects. The extended-release formulation may cause prolonged effects of both alcohol and propranolol, which can lead to an increased risk of adverse reactions.

Your approach to omit the evening dose of immediate-release propranolol when consuming alcohol is a common strategy, but it’s important to note that this might not be advisable with the extended-release formulation, as it has a different release mechanism.

Next Steps:

  1. Consider Moderation: If you decide to consume alcohol, limit your intake and monitor how you feel. Stick to lighter options and consider having only 1-2 drinks in a longer timeframe, just as you did previously.
  2. Stay Hydrated: Drink plenty of water alongside any alcoholic beverages to help reduce potential side effects.
  3. Watch for Side Effects: Pay attention to how your body reacts. If you feel excessively dizzy, drowsy, or notice any unusual symptoms, it may indicate that alcohol isn't compatible with your current medication regimen.
  4. Keep a Log: Write down any experiences when mixing alcohol and propranolol to track your reactions over time. This log can also guide future decisions about drinking.
  5. Communicate with Your Provider: If you have concerns about how propranolol interacts with alcohol, consider discussing this with your healthcare provider for personalized guidance specific to your treatment plan.

Always prioritize your health and safety when it comes to medication and alcohol consumption. If you have any further questions or need more support, feel free to ask.

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