OpenHealth Q&A

Get answered by medical professionals

Significant Fluctuations in Pupil Size

12/13/2025, 7:20:21 PMMale25-34

Subject M17 raises a question about the variations occurring in their pupil size. While minor pupil changes are typically viewed as standard, the fluctuations experienced are notably pronounced. The process involves a rhythmic transition from a reduced size to expanded, then to an average size, and back to enlarged, repeating this cycle. Uncertainty arises about whether such behavior is typical, as there seems to be no similar pattern in others’ eyes. This observation began approximately six months ago, alleviating immediate concern. Additionally, there have been no noticeable alterations in vision quality.

Internal MedicineEndocrinology

Answers (1)

Cony

12/13/2025, 7:20:36 PM

OpenHealth AI

The patterns of varying pupil sizes you're observing can be concerning but may be quite normal in some contexts. Pupil size can fluctuate in response to a range of factors such as light levels, emotional state, and certain stimuli.

Understanding Pupil Behavior:

  1. Normal Variations: Pupil size can change due to the autonomic nervous system's response to light, near or far vision, and even emotions. These shifts are usually subtle.
  2. Significant Changes: Pronounced and rhythmic variations, especially if they are not linked to environmental factors or emotional responses, might indicate a neurological or physiological condition that should be evaluated.

Next Steps:

  1. Monitor Your Symptoms: Keep a record of when these fluctuations occur. Note any triggers, duration, and whether they happen in specific light conditions.
  2. Avoid Irritants: Reduce exposure to bright lights and stressors that could be causing the pupils to react strongly.
  3. Schedule a Routine Eye Exam: While you mentioned good vision quality, it's essential to consult an eye care professional, especially because this pattern has been persisting for six months.
  4. Consider Other Symptoms: If you ever notice changes in your vision, headaches, or other unusual sensory experiences, it’s crucial to seek professional advice immediately.

It’s understandable to feel uncertain about these changes. By monitoring the situation and taking the steps above, you can gain clarity on whether there's a need for further evaluation. Let me know if you have any other questions or specific concerns!

Related Questions

Experiencing Uncertainty: Possible Ischemic Attack?

Greetings, everyone, including healthcare professionals. For the past year, I've been managing high blood pressure, and I'm currently prescribed a regimen that includes Amlodipine at 10 mg and Bisoprolol at 5 mg. At 44 years old, I’m a woman who is classified as overweight and also deals with hypothyroidism, low ferritin levels, liver issues, and slightly elevated cholesterol levels. Typically, my medications maintain my blood pressure within a range of 110/70 to 140/80. However, two days ago, I experienced a stressful episode, causing my systolic pressure to spike to 155/95. Upon standing, I sensed weakness in my left arm, which felt as if it were slightly twisting. A wave of panic hit me, and I feared I might be incapacitated or having a stroke. Despite my anxiety, I was still able to grasp a glass and tightly close my fist. Briefly, my right arm felt a mild sensation that lasted only a second. This peculiar feeling persisted for roughly a minute. I then consumed some mint tincture mixed with alcohol and engaged in deep breathing exercises, which remarkably alleviated my symptoms and brought my blood pressure back to a stable level. I contacted my physician, who inquired about my symptoms and their duration. Aside from the discomfort in my arm, I wasn't experiencing any additional issues. A second doctor relieved me of any immediate concerns regarding the necessity for an MRI, and since I underwent one a month prior that showed no abnormalities in my cranial blood vessels, I felt some reassurance. Now, back home and with lingering fears of having experienced an ischemic attack, I wonder if an ultrasound of the neck arteries is warranted. Do my symptoms indicate a potential attack? What steps should I take next? Has anyone faced a similar situation? Thank you all for your insights.

HypertensionThyroid DisordersEndocrinology
Male25-34
7 minutes ago

Micronodules Detected in Lung

Hello, I recently underwent a coronary artery calcium (CAC) scan to assess arterial plaque, and I was pleased to receive a favorable score of 7.75. However, the report highlighted the presence of several clustered micronodules located in the right upper lung, accompanied by adjacent ground-glass opacities. I am a 60-year-old male, 6 feet tall and weigh 190 pounds. I do not currently take any medications and generally enjoy excellent health. There is a family history of heart disease on my father's side. Additionally, I am a non-smoker, apart from occasional use of cannabis, and consume alcohol very infrequently. Thank you in advance for any insights you can provide!

AsthmaCOPDInternal Medicine
Male25-34
37 minutes ago

Liver Mass Assessment

Patient Profile: - Age: 61 years - Height: 5'9" - Weight: 240 lbs - Gender: Female - Lifestyle: Non-drinker, non-smoker, no illicit drugs Current Medications: - Atenolol 10mg (morning and evening) - Rosuvastatin 40mg (evening) - Duloxetine 60mg (evening) - Spironolactone 25mg (recently added) - Jardiance 10mg (recently added) Medical History: The patient has a notable history of multiple pheochromocytomas and paragangliomas, having undergone surgery on eight occasions. According to scans performed three years ago, two subcentimeter retroperitoneal masses were identified, suggestive of potential paraganglioma. Additionally, she suffers from secondary polycythemia and possesses the PHD1 gene mutation. Previously, she received treatment at a prominent research institution in the United States. However, her endocrinologist has since retired and returned to their home country. Current Condition: At present, she is mostly asymptomatic. However, in January 2026, she experienced a concerning event requiring an ambulance transport to a local emergency room, where her oxygen levels registered at 88-89%. This incident was unsettling, given her extensive medical history. The emergency physician initially diagnosed her with congestive heart failure (CHF), but upon discharge, her family medicine doctor suggested pneumonia. During her hospital stay, a cardiologist—who has never managed a pheochromocytoma patient—recommended a chemical stress test. A CT scan performed on her chest revealed a 3.2 x 2.5 cm mass located in the left lobe of her liver. Her blood tests typically show elevated levels related to pheochromocytomas; however, the laboratory does not conduct resting catecholamine testing, which leads to unreliable results, despite them being consistent over time. Furthermore, she has received care at major hospitals in Minnesota and both leading hospitals in Cleveland, Ohio. Unfortunately, when she required her last surgery, the tumor board declined her case, citing an unfavorable risk-benefit ratio. This leaves her without a specialist in pheochromocytomas. Request for Guidance: The patient is seeking advice or recommendations for her current health situation and management of her conditions.

Crohn's DiseaseThyroid DisordersEndocrinology
Male25-34
1 hour ago

Navigating the Complexity of Symptoms: Is It PCOS or Something Else?

While I’m not an expert in self-diagnosis, I find myself puzzled by an array of symptoms that overlap, making it challenging to pinpoint what might be affecting my health. Let's break down my situation: - Age: 25 years, Gender: Female, Height: 5’1”, Weight: 125 lbs. - The last menstruation occurred in June 2024. Prior to this, my menstrual cycle was remarkably consistent since I was around 12 years old, typically without severe premenstrual symptoms, heavy flow, or irregularities. - Various blood tests over time reveal that most hormone levels fall within normal ranges, with the exception of estradiol (persistently between 10-20) and progesterone (remaining below 0.2). - A couple of results raised some concerns for me personally, even if my doctors weren’t alarmed: my morning cortisol was measured at 13.4 and in the afternoon at 9.49. One test indicated a TSH level of 2.35, which increased to 3.93 months later. My fasting glucose consistently hovers around 80, whereas random glucose levels were recorded at 68, and postprandial glucose was 65. - An MRI indicated a "deviation of the pituitary stalk, potentially linked to a small pituitary adenoma." - An ultrasound revealed "multiple oval, well-defined, anechoic images with posterior acoustic enhancement, measuring a few millimeters, located around the edges of the stroma." - The symptoms I am experiencing include disrupted sleep (frequent awakenings, particularly around 3 AM, making it hard to resume sleep), lack of energy, difficulty in weight management, persistent hunger, heightened anxiety, and hair thinning. - Birth control (drospirenone and ethinyl estradiol) exacerbated nearly all of my symptoms, leading me to discontinue use after two weeks despite experiencing a withdrawal bleed. - My lifestyle is generally healthy; I consume a lot of whole foods, engage in weightlifting, and run regularly. Given that I’ve received a diagnosis of PCOS, I’m wondering if this assessment seems accurate. What options do I have moving forward, especially since the contraceptive method didn’t provide relief and I appear to exhibit signs of additional complications such as thyroid issues or cortisol dysregulation?

LupusThyroid DisordersEndocrinology
Male25-34
2 hours ago

A Mysterious Illness That Resembles Strep Throat

As an 18-year-old college student, standing at 5'4" and weighing 140 pounds, I maintain an active lifestyle. I do not smoke or have any preexisting health issues, aside from the vitamins and supplements I take daily. Approximately five days ago, I began to feel unusually fatigued and achy. Within just a day, my symptoms escalated to include a high fever reaching between 101°F and 102°F that ibuprofen couldn’t seem to alleviate. I experienced extreme tiredness that kept me bedridden all day, along with a persistent headache and intense throat pain, which was compounded by swollen lymph nodes and the familiar white patches often associated with strep throat. Having dealt with strep throat before, I recognized a need for antibiotics. Two days into feeling unwell, I visited an urgent care facility for an assessment and received a rapid strep test, which unfortunately came back negative. I recalled a previous incident where my rapid strep test also indicated a false negative, only for the culture sent for further testing to confirm the presence of strep bacteria. Given my symptoms and the findings from the examination, the healthcare provider prescribed Cefdinir, as I am allergic to amoxicillin, despite the negative rapid test results. The antibiotics proved effective, and I felt nearly back to normal, leading me to believe that my culture results would also come back positive for strep, suggesting a recurrence of my previous infection. However, I received the culture results yesterday, and to my surprise, they came back negative for strep. While I lack medical expertise, I’ve been led to believe that false negatives in cultures are exceedingly rare. Now, I find myself puzzled about what kind of bacterial infection I might have had if it wasn’t strep. Any insights or information regarding my situation would be greatly appreciated. Thank you!

ArthritisCrohn's DiseaseEndocrinology
Male25-34
2 hours ago