Seeking Guidance on HIV Risk While Using PEP (Viropil)
Greetings, esteemed medical professionals. I am a 25-year-old male, approximately 175 cm tall, weighing around 62 kg, and I don’t smoke. On September 5th, I engaged in sexual activity with a sex worker, ensuring the use of a condom. However, I later discovered minor cuts at the base of my penis where the condom did not provide complete coverage, which raised concerns about potential exposure. I commenced post-exposure prophylaxis (PEP) with Viropil within 36 hours following the encounter. I have no significant prior medical issues and currently do not exhibit any symptoms related to my situation. I reside in India and, regrettably, there are no local healthcare professionals available to assist with this PEP treatment in my small town. Thus, I am self-administering the medication. I am also undergoing regular tests for liver and kidney function. Are there any additional supportive medications I should consider? I am experiencing some side effects, including a sore throat and itching.
Answers (1)

9/13/2025, 6:01:30 PM
OpenHealth AI
It sounds like you are taking proactive steps after your potential exposure to HIV by starting post-exposure prophylaxis (PEP) with Viropil, and you are monitoring your health closely. Here’s a clear overview addressing your situation:
Main Points:
- Continued PEP Compliance: It’s crucial to take PEP as prescribed for the full 28 days, even if you are not experiencing severe symptoms.
- Managing Side Effects: Mild side effects like a sore throat and itching can occur. It’s important to address these while continuing your PEP.
- Monitoring Health: Regular checks on liver and kidney function are essential during PEP, especially when self-administering.
Explanation:
You experienced a potential risk of HIV exposure during your encounter, but using a condom significantly reduces that risk. Starting PEP within 36 hours was a good decision, as it is most effective when initiated as soon as possible after potential exposure.
While taking PEP, some individuals report side effects, such as a sore throat or itching. These are often manageable, but it’s wise to monitor their intensity and persistence.
Next Steps:
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Continue PEP Treatment: Make sure to take the full 28 days of Viropil as prescribed. Missing doses can increase the risk of PEP failure.
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Manage Side Effects:
- For your sore throat, try throat lozenges, warm salt water gargles, or over-the-counter pain relievers (like paracetamol) if they’re suitable for you.
- For itching, consider antihistamines or calamine lotion, but be cautious about mixing medications.
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Stay Hydrated: Drink plenty of fluids, as hydration can help with general malaise and any side effects.
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Monitor Symptoms: Keep track of any new symptoms or changes in your health. If symptoms worsen (such as a fever or severe rash), consider reaching out to a healthcare provider.
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Follow-Up Testing: After completing the 28-day PEP course, it’s important to have an HIV test at the appropriate time (usually at 4-6 weeks after completing PEP) to confirm your status.
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Seek Local Resources: If possible, look for telehealth consultations or nearby clinics for further support, as they may provide additional guidance and testing opportunities.
Remember, you are taking the right steps, and it’s important to prioritize your health and wellbeing throughout this process. If you have any concerns or need additional support, I encourage you to find resources that can provide assistance.
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