Can the Tdap Vaccine Result in Persistent Swelling of Lymph Nodes?
For the past few weeks—approximately three to four—I have noticed a lymph node in my neck that has become enlarged. To address my concerns, I visited my primary care physician, who conducted a thorough examination along with some tests. Fortunately, all the results returned normal, and my doctor was not overly worried since I do not have any accompanying symptoms. Notably, this swelling occurred on the same side where I received my Tdap vaccine at the end of July. Is it plausible for the vaccine to still be causing this swelling? I can't help but spiral into darker thoughts after searching online, leading me to worry about conditions like lymphoma.
Answers (1)

9/13/2025, 8:10:37 PM
OpenHealth AI
It's understandable to feel concerned about persistent swelling in your lymph nodes, especially after having received the Tdap vaccine. While it’s unlikely that a vaccination given several months ago would be the cause of ongoing lymph node swelling, localized swelling shortly after vaccination can happen as the immune system responds.
Explanation
Your lymph nodes can swell for several reasons, including infections, inflammation, or responses to vaccines. The Tdap vaccine can cause temporary swelling in nearby lymph nodes, but typically, this should resolve within a few weeks. Since you mentioned that your doctor performed a thorough examination and found normal results, this is reassuring.
Next Steps
- Monitor the Lymph Node: Keep an eye on the swelling; note any changes in size, consistency, or if you develop any new symptoms like pain, fever, or night sweats.
- Hydration and Care: Stay hydrated and maintain a healthy diet to support your immune system.
- Limit Online Searches: While it’s natural to seek information, excessive searching can increase anxiety. Focus on information from reputable sources instead.
- Check-in with Your Doctor: If the swelling doesn’t improve in the next few weeks, or if you notice any concerning symptoms, consider following up with your doctor for further evaluation.
Remember, it is common for lymph nodes to swell for benign reasons, and the previous evaluation bringing normal results is a strong indicator that serious conditions are less likely. Being mindful of your health while also trying to remain calm can help significantly. Let me know if you have any other questions or need further clarity!
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