Assessing the Risk of Overlooking Endometrial Cancer
Age 33, female. Over the past half year, I have endured excruciatingly heavy menstrual bleeding, prolonged periods, and unexpected bleeding during intercourse, as well as post-menstrual bleeding. What troubles me most, however, are the enormous clots resembling golf balls that I am passing; they are frightening and deeply distressing. I sought medical attention at the hospital, where an endometrial biopsy was conducted, returning with normal results. Yet, the biopsy revealed a thickened lining. Furthermore, both my cervical examination and smear test indicated no abnormalities. I've consulted with two specialists; one detected signs of polycystic ovary syndrome (PCOS) via ultrasound, while the other dismissed this diagnosis, particularly since I have had two successful pregnancies without complications. Given that my sister and both of my cousins have been diagnosed with PCOS, I feel there could be a possibility of it affecting me too. Is it plausible for PCOS to cause such alarming blood clots? Or is there a concern that cancer could have been overlooked? This dramatic shift in my health occurred suddenly after childbirth, and prior to my pregnancy, I never faced anything like this. It's an incredibly distressing situation to be in.
Answers (1)

9/2/2025, 7:01:42 PM
OpenHealth AI
It sounds like you're facing a challenging and distressing situation regarding your menstrual health, and it's understandable to have concerns about the symptoms you've described. Let's break down your concerns and focus on the facts.
Main Points:
- Heavy menstrual bleeding with large clots can be alarming, but it can occur for several reasons, including hormonal imbalances like PCOS.
- Normal biopsy results and other tests help rule out more serious conditions like endometrial cancer.
- It’s important to continue monitoring your symptoms closely and discuss any changes with your healthcare provider.
Explanation:
Heavy menstrual bleeding and passing large clots can happen for various reasons. Conditions like polycystic ovary syndrome (PCOS) can cause hormonal fluctuations leading to unpredictable menstruation patterns. The fact that your biopsy was normal is reassuring, as it suggests that cancer is less likely.
Your heavy bleeding and large clots are likely related to hormonal imbalances, which can be influenced by PCOS, especially if there’s a family history. It’s not uncommon for menstrual patterns to shift after childbirth, so your current experience may be a new normal that requires further management.
Next Steps:
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Track Your Symptoms: Keep a detailed diary of your menstrual cycle, noting the intensity of bleeding, the presence of clots, pelvic pain, and any other symptoms. This information will be valuable for your healthcare provider.
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Seek a Specialist Opinion: If you haven't already, consider consulting a gynecologist specializing in menstrual disorders or reproductive endocrinology. They may recommend additional tests or treatments based on your history and symptoms.
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Discuss Treatment Options: If PCOS is confirmed or suspected, discuss management strategies that may include lifestyle changes (diet, exercise), hormonal treatments (like birth control), or medications that can regulate menstruation.
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Monitor for Changes: Watch for any concerning symptoms, such as severe pain, fever, changes in bleeding patterns, or other unusual changes. If these occur, seek immediate medical advice.
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Consider Mental Health Support: It's normal to feel anxious when dealing with complex health issues. Consider talking to a counselor or support group that specializes in women's health to help cope with stress and emotional impacts.
Your health concerns are valid, and it’s essential to continue exploring them with a healthcare provider. You're not alone in this, and support is available to help you through.
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