Persistent Throat Infections: Seeking Answers
At 31 years old, I am a woman, standing 5 feet 3 inches tall and weighing 107 pounds. I do not smoke, and I’m not on any medications, nor do I have any notable medical history. In late July, while visiting Romania from my home in the US, I developed a painful sore throat that made swallowing difficult. The discomfort was localized to my left side, accompanied by fever and chills. Noticing white patches in my throat, I sought medical attention at a hospital on August 2, concerned it might be strep throat. Although the strep test returned negative, the doctor prescribed me a 7-day course of amoxicillin. Remarkably, I experienced significant relief the following day, and the symptoms subsided while I was on the antibiotics. After completing the course on August 8, I was disheartened to find myself facing similar symptoms by August 13, this time affecting the right side of my throat. I visited urgent care, where both strep and COVID tests yielded negative results. The provider suspected a viral infection and advised me to rest. However, when my fever persisted and wouldn’t respond to Tylenol or Advil, I returned the next day. They ruled out mononucleosis with a negative test and sent another strep test for further analysis, which also came back negative. The doctor then prescribed me a 10-day supply of amoxicillin along with a steroid (methylprednisolone), and I noticed an improvement within 24 hours—my fever disappeared and my throat began to improve. After finishing the antibiotics on August 24, I awoke on August 27 to find that the same left-sided throat pain had returned. What could be the underlying issue here, and what additional tests might be beneficial for me?
Answers (1)

8/27/2025, 6:02:55 PM
OpenHealth AI
It sounds like you've been through a challenging experience with recurring throat infections, and it's understandable to be concerned about the persistent symptoms. Your description suggests that you may be dealing with a lingering issue that could be related to either recurring infections or inflammation. Let's break this down.
Main Points:
- You have experienced recurrent throat pain, despite negative tests for common infections.
- It's possible that an underlying cause such as chronic inflammation, allergy, or other conditions could be contributing to your symptoms.
Explanation:
Given your history, the initial bacterial infections seem to have responded well to antibiotics, indicating a possible bacterial component. However, the recurrence after finishing the antibiotics suggests that there could be more to the issue. Factors such as viral infections, allergies (e.g., to environmental triggers or foods), or even conditions like chronic tonsillitis or gastroesophageal reflux disease (GERD) might play a role.
Next Steps:
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Continue Monitoring Symptoms: Keep a journal of your symptoms, noting when they occur, their severity, and any triggers. This can provide valuable information for identifying patterns.
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Consider Allergy Testing: If you suspect that allergies might be contributing to your symptoms, it may be worthwhile to explore allergy testing, as they can cause recurrent throat inflammation.
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Hydration and Warm Gargles: Keep hydrated, and try warm saltwater gargles to soothe irritation in your throat. This can provide immediate relief while you investigate further options.
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Consult with a Specialist: Given the persistent nature of your symptoms, it may be beneficial to consult an Ear, Nose, and Throat (ENT) specialist. They might recommend imaging studies like a throat ultrasound or a more specific examination to rule out other potential causes.
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Lifestyle Considerations: Make sure to focus on eating a balanced diet and getting adequate rest, as overall health supports the immune system and can aid recovery.
Please keep a close watch on how your symptoms evolve, and don’t hesitate to seek further medical evaluation if your condition does not improve or worsens. I hope you find relief soon! Let me know if you have any more specific questions or need additional guidance.
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