Persistent Swelling near Submandibular Gland After Two Years: Any Reasons for Alarm?
I am a 25-year-old female who generally considers herself to be in good health. Standing at 5 feet 5 inches tall and weighing 165 pounds, I don’t smoke or drink alcohol. My lifestyle includes regular exercise and adherence to a plant-based diet, and I am not taking any medications. About two years ago, I experienced the flu, which was shortly followed by a salivary gland infection in my submandibular gland. The inflammation was so severe that there was virtually no distinction between my chin and neck during that time. Fortunately, the swelling subsided after I received a course of high-dose steroids coupled with antibiotics. However, since that incident, I have continued to notice localized swelling in that region, specifically a lump directly at the site of the original inflammatory episode. The lump has a smooth surface and is about the same firmness as the tip of my big toe — an unusual metric, I know, but it's the best comparison I can devise. Initially, I consulted an ear, nose, and throat specialist, underwent various ultrasounds, and had a needle biopsy performed. The specialists informed me that the biopsy might exhibit elevated levels due to the lymph node being reactive; yet, the results ultimately returned as normal. Although I no longer need to see that specialist, the swelling persists in the same area. I suspect the lymph node behind my submandibular gland is the root of the swelling, which might be causing the sensation of enlargement in the gland itself. Lately, I've noticed a slight increase in the size. Should I be worried about the potential for lymphoma or any other forms of cancer? I'm feeling quite bewildered and anxious, as it’s frustrating to have persistent swelling in that area two years after my initial infection.
Answers (1)

8/27/2025, 8:38:24 PM
OpenHealth AI
It's understandable to feel concerned about a persistent lump in your submandibular region, especially after your past experiences with infections. Given your description, it's essential to address your concerns and provide you with clear guidance.
Main Points:
- Persistent swelling after an infection can be common due to reactive lymph nodes.
- Continuous monitoring of the lump is crucial, especially if you notice changes in size or consistency.
- There are steps you can take to manage your anxiety and ensure you're addressing the situation appropriately.
Explanation:
The swelling you're experiencing may be due to the reactive nature of the lymph node following your submandibular gland infection. It's not unusual for lymph nodes to remain enlarged for an extended period after inflammation, especially if they had been previously compromised. Since your biopsy results returned normal, the likelihood of something more serious like lymphoma is lower, but your concern is completely valid, and it's good to stay vigilant.
Next Steps:
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Monitor Changes: Keep an eye on the lump and note any changes in size, firmness, or if it becomes painful. A diary can help track these changes over time.
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Self-Care: Maintain a healthy lifestyle, focusing on a balanced diet and hydration. Some people find warm compresses can provide comfort to the area, but ensure they are not excessive in temperature.
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Regular Check-ins: Set a specific timeline (e.g., every 3-6 months) to reassess the lump. If you notice rapid changes or develop new symptoms like fever or significant pain, this should prompt more immediate attention.
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Consider a Second Opinion: If your anxiety persists or the lump grows noticeably, seeking a second opinion from another specialist, such as a different ENT or a surgeon specializing in head and neck conditions, could provide you with further reassurance or different perspectives.
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Emotional Support: Managing anxiety about health issues can be challenging. Consider reaching out to friends or family, or even counseling, if it helps you cope with the emotional aspects of your concern.
You're taking good steps by seeking information and being proactive. If you have further questions or need clarification as you navigate this, please feel free to ask.
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