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Can Fluid Retention Lead to Cysts?

8/13/2025, 3:31:32 PMMale25-34

Hello, I'm a 20-year-old female diagnosed with fibromyalgia and ME/CFS, and there's the possibility of endometriosis as well. For nearly three years, I've been on gabapentin at 400 mg three times a day and using birth control pills. Additionally, I’ve recently started taking fluoxetine. I maintain a healthy weight, and I don’t consume alcohol, smoke, or use drugs. I work five days a week and am not bedbound. About two years ago, I experienced a severe pilonidal cyst that was incredibly painful, rendering me nearly immobile due to the agony, which is quite a feat for someone already living with fibromyalgia. Antibiotics initially resolved it, but it returned less than a year later and proved unresponsive to medication, leading to a painful surgery to drain it. The surgeons found something atypical about it, but they did not elaborate. I believe it was because it was entirely under the skin with no visible opening. I then faced the long ordeal of daily wound care until it healed into a small scar. Currently, I'm feeling overwhelmed because a new painful lump has developed near the scar site, and the thought of repeating this experience is distressing. I've taken extensive preventive measures, such as avoiding shaving to reduce irritation and ingrown hairs and keeping the area clean and dry. I limit pressure on that area, and I’ve avoided swimming and cycling. I’m gearing up to start university in September, and I’ve finally begun to rebuild my life after the challenges posed by fibromyalgia and CFS. This situation feels like it could derail everything I have worked to restore, and I fear facing this issue for the long term. It has been less than six months since my previous wound healed. I’m at my wits’ end and curious whether my gabapentin or birth control pills could be contributing factors. I have read they may cause fluid retention; could this potentially lead to abscesses or cysts?

ArthritisMultiple SclerosisFibromyalgia

Answers (1)

Cony

8/13/2025, 3:32:22 PM

OpenHealth AI

Fluid retention and the development of cysts or abscesses can indeed be concerning, especially when you've had painful experiences in the past. However, based on what you’ve described, the connection between fluid retention caused by gabapentin or birth control pills and the formation of cysts is not straightforward.

Key Points:

  1. Fluid Retention: Both gabapentin and some hormonal birth control methods can potentially cause fluid retention in some individuals. However, this fluid retention typically does not directly lead to cysts or abscesses.

  2. Cyst Formation: Cysts, like the pilonidal cyst you've experienced, often occur due to blocked glands or hair follicles, infections, or injury to the area. It’s possible that factors such as pressure, moisture, and skin irritation in that region may be contributing to the new lump you're noticing.

  3. Current Symptoms: Given your history with pilonidal cysts, it’s understandable to feel anxious about new lumps or painful areas, especially as you prepare for university. This is valid and understandable, and addressing your concerns is essential.

Next Steps:

  1. Self-Monitoring: Keep an eye on the new lump's size, pain level, and any associated symptoms (like redness or drainage). If it increases in size, becomes more painful, or shows signs of infection (such as warmth or fluid), it may need immediate attention.

  2. Preventive Care:

    • Hydration: Ensure you maintain proper hydration, as it may help reduce fluid retention.
    • Hygiene: Continue your good practices of keeping the area clean and dry. Consider using a gentle exfoliating wash in the area to help prevent blockages.
    • Clothing: Opt for loose-fitting clothing to minimize friction and pressure on the targeted area, as this can help reduce irritation.
  3. Pain Management: If you are feeling discomfort, consider using a warm compress on the area to help with pain relief and to enhance circulation, which may reduce inflammation.

  4. Stay Calm and Informed: Understand that while cysts can be painful and frustrating, they are manageable. If you feel overwhelmed, reach out to support groups where you can talk about your experiences with fibromyalgia and your concerns regarding cysts.

  5. Documentation: Keep a record of your symptoms, including any new developments and responses to your current treatments. This can be useful for future discussions with a healthcare provider.

If the lump persists or worsens, or if you have any new symptoms, please reach out for professional advice as targeted treatment might be necessary. Remember, addressing your concerns early is crucial to preventing larger issues in the future. You're making great strides in rebuilding your life, and it’s important to prioritize your health as you embark on this new chapter.

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