Seeking Insights on Eye Movement Issues for My Mom
I am reaching out to gather some perspectives on behalf of my mother, who is 63 years old and has been experiencing persistent issues with her eye movements. She is not on any prescription medications, relying instead on dietary supplements, and is generally in good health aside from being a smoker. Currently, one of her eyes is referred to as a "lazy eye," while the other eye fails to cross the midline. Medical professionals suspect a possible muscle dysfunction, possibly of a neurological origin. They have proposed that conditions such as myasthenia gravis (MG) or certain mitochondrial disorders like progressive external ophthalmoplegia (PEO) might be at play. My mother has consulted with a neuro-ophthalmologist and a pediatric ophthalmologist, and she is set to visit a specialist in Chicago tomorrow. She is curious whether surgical intervention could be an option for her. Here’s a summary of her situation: - The primary concerns are ocular, characterized by restricted eye movement and misalignment. - There is no significant overall muscle weakness identified. - A thymoma has not been confirmed. - There is speculation that this could stem from an autoimmune condition or a genetic factor, but no definitive diagnosis has been reached yet. Additionally, it’s important to mention that she underwent cataract surgery in her early 40s and had a cosmetic procedure to correct droopy eyelids that was not successful. Since that poorly done surgery, she has been favoring one eye in an effort to mitigate double vision. We’re left to ponder whether this longstanding habit of relying on one eye could have led to weakness in the other, which now manifests as laziness. We’re also questioning if this might have contributed to the current eye movement problems. I have several questions that I hope the community can help with: 1. Is it possible for MG or mitochondrial disorders, like PEO, to manifest at the age of 63? 2. What methods do physicians use to distinguish between late-onset MG and mitochondrial diseases? 3. Has anyone had experience with oculomotor symptoms that remain relatively stable, rather than fluctuating as is typical for MG? 4. If MG is diagnosed, might a thymectomy still be advisable at her age? Any insights, shared experiences, or tips on questions to pose to her neurologist would be immensely valuable as we prepare for this upcoming appointment. We are eager to be as well-informed and equipped as possible. Thank you for your assistance!
Answers (1)

8/13/2025, 1:40:56 AM
OpenHealth AI
Main Points: Your mother is experiencing complex eye movement issues that may be related to neurological or muscular conditions. You're right to seek clarity before her upcoming appointment with the specialist. Let’s address your primary concerns and provide actionable steps.
Explanation:
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Possible Conditions: Myasthenia gravis (MG) can indeed present in individuals over 60, although it’s more commonly diagnosed in younger adults. Mitochondrial disorders like progressive external ophthalmoplegia (PEO) can also manifest in later life, but they tend to have distinct clinical features.
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Diagnosis Distinctions: Physicians typically use a combination of tests, including blood tests (to check for anti-acetylcholine receptor antibodies in MG), imaging studies (like CT scans for thymoma), and neurologic examinations to differentiate between MG and mitochondrial disorders.
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Oculomotor Symptoms: It’s common for MG symptoms to fluctuate, but some patients can experience more stable symptoms. This is one reason your mother’s neurologist will conduct a thorough evaluation to establish the diagnosis.
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Thymectomy Considerations: If MG is confirmed, a thymectomy may still be considered beneficial, even at 63, especially if she has symptoms that could improve with surgery; various factors, including overall health and presence of a thymoma, will influence this decision.
Next Steps:
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Prepare for the Appointment: Make a list of observations regarding her symptoms, any changes over time, and experiences from previous consultations. This information can help guide the specialist's assessment.
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Questions for the Specialist: Consider asking the following:
- What specific tests will be performed to confirm the diagnosis?
- How do our observations about her eye movement relate to each potential diagnosis?
- What are the potential benefits and risks of a thymectomy at her age if MG is diagnosed?
- Could her history of favoring one eye contribute to her current symptoms?
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Lifestyle Adjustments: Encourage her to monitor her eye strain and rest her eyes regularly, which may alleviate some discomfort while you await a clearer diagnosis.
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Smoking Cessation: If possible, support her in considering quitting smoking, as it could benefit her overall health and any potential treatment options.
By actively engaging in her care, asking informed questions, and supporting her health choices, you can help foster a better understanding of her condition and treatment pathways. Please feel free to reach out with any further questions or if you need additional information after her appointment.
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