Seeking Answers: The Complexity of PMDD, Fatigue, and Anxiety
Hello everyone! I find myself navigating a series of persistent symptoms that significantly diminish my quality of life, and I'm eager to uncover their underlying causes. I experience intense anxiety related to medical settings and a fear of blood, which often leaves me feeling immobilized during consultations with healthcare professionals. As a result, I'm trying to approach these visits better prepared. Here’s a brief overview of my situation: - Age: 35, Female - Current Medications/Supplements: None I suffer from debilitating symptoms of premenstrual dysphoric disorder (PMDD), which surfacing just before my menstrual cycle brings about severe mood swings, depression, irritability, and a sense of hopelessness. These fluctuations have led me to make drastic decisions, like quitting jobs or ending relationships in the days leading up to my period. Despite trying a variety of medications—including numerous SSRIs, SNRIs, trazodone, klonopin, different types of benzodiazepines, and various other common antidepressants—the results have been disappointing. Even outside of my luteal phase, I contend with relentless fatigue. Additionally, I frequently experience brain fog, which manifests as difficulties with focus, memory lapses, and an overall feeling of mental sluggishness. My generalized anxiety tends to vary but presents itself as a physical response rather than one rooted solely in situational factors. I have battled with mood and hormonal disturbances since my early teenage years, but it wasn't until I began journaling that I recognized a clear pattern in my experiences. I meticulously track my menstrual cycle and have observed pronounced fluctuations during ovulation and the luteal phase. At this moment, I am not on any hormonal contraceptives, having discovered early on that they exacerbated my issues. My primary concern is the strong instinct that what I'm facing extends beyond mere anxiety or depression, yet my healthcare providers often dismiss my suspicions, merely treating me as though those are the sole culprits. I am seeking advice on what specific tests to request in order to engage in a more fruitful dialogue with my physician. When attempting to arrange for hormone blood tests, I face considerable challenges due to my intense fear of blood. This anxiety necessitates extensive preparation prior to the appointments, often scheduling them when my partner can accompany me for reassurance. On my last attempt, I was disheartened to learn from the nurse that the hormone tests might not be covered by my insurance, and I only received this information after getting there. The process took an immense amount of courage for me to initiate, which made the rejection all the more frustrating. Over a year has passed since that experience due to my hemophobia, and I'm finally mustering the courage to consider pursuing a new blood test. I welcome any thoughts or suggestions you might have on my situation!
Answers (1)

8/2/2025, 4:50:49 AM
OpenHealth AI
It sounds like you're dealing with a complex interplay of symptoms affecting both your mental health and overall well-being. This is understandably frustrating, especially since you feel your concerns may not be fully addressed by your healthcare providers. Let’s break down your situation and explore some actionable steps forward.
Main Points:
- You’re experiencing severe PMDD symptoms, fatigue, and anxiety, which have been challenging to manage.
- You wish to engage your healthcare provider more effectively and explore potential testing for hormone-related issues.
- You face significant anxiety related to medical settings, particularly blood tests.
Explanation:
Premenstrual Dysphoric Disorder (PMDD) can significantly impact your mood and decisions due to hormonal fluctuations and can be compounded by underlying anxiety and fatigue. Since you've documented your symptoms and tracked your menstrual cycle, you have valuable insights into how these cycles influence your emotional and physical health. Addressing your symptoms holistically—considering both hormonal and psychological factors—may be beneficial.
Given your experience with various medications, you might also want to explore lifestyle modifications and additional therapies that can help manage your symptoms. It's important to have a productive dialogue with your doctor about potential causes and treatments, as well as what tests might provide useful information.
Next Steps:
-
Prepare for Your Next Appointment:
- Create a Symptom Journal: Continue documenting your mood, symptoms, and their correlation with your menstrual cycle. Include your experiences of fatigue and anxiety. This can help create a clearer picture for your provider.
- List Specific Tests: Consider requesting tests such as:
- Hormonal levels (like estrogen, progesterone, and perhaps thyroid function tests).
- Adrenal function (like cortisol levels).
- Other relevant blood tests that might indicate vitamin deficiencies (e.g., Vitamin D, B12).
-
Plan Around Your Anxiety:
- Accompaniment: It’s great that you can bring someone for support. Continue doing this for your next appointment to help lower anxiety.
- Communicate Needs: When scheduling, let the office know about your hemophobia so they can help accommodate you and provide reassurance.
-
Consider Supportive Therapies:
- Cognitive Behavioral Therapy (CBT): This can be effective in managing both anxiety and the mood swings associated with PMDD. It may also help ease your fear of blood and medical settings.
- Mindfulness Techniques: Incorporating mindfulness or relaxation techniques can help manage anxiety in general and may even assist during medical appointments.
-
Explore Lifestyle Adjustments:
- Regular exercise, a balanced diet, sufficient sleep, and hydration can contribute to overall well-being and may mitigate some PMDD symptoms. Prioritize self-care practices that make you feel good and help manage fatigue.
While navigating these challenges may feel daunting, remember to take one step at a time. If you encounter difficulties with tests or treatments, keep advocating for your needs. Your insights and observations are valuable, and partnering with a supportive healthcare provider can enhance your journey toward better health. If you’d like, I can provide more tailored resources or coping strategies as you prepare for your appointments.
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