27-Year-Old Woman Experiencing Weight Loss, Fatigue, and Other Symptoms Seeking Advice
Hello everyone, I'm reaching out to see if anyone has had experiences similar to mine or can provide some advice. Lately, I’ve been feeling quite unwell, and I'm in need of some direction. I’m a 27-year-old woman, standing 5’7” and weighing 142 lbs at the moment. Over the past four months, I’ve lost weight unexpectedly, as I usually maintain a weight between 150 and 160 lbs. My activity level is moderate, largely consisting of walking for my job, although I don’t regularly engage in gym workouts. Here are the symptoms I’ve been encountering: - **Persistent fatigue:** On my days off, I sleep over 12 hours and still wake up feeling drained. - **Increased hair loss:** I’ve noticed more hair falling out than normal. - **Bruising easily:** I have always bruised easily, but the occurrences have become more pronounced lately. - **Cognitive fog:** Many days, I feel absent-minded and as though I'm merely going through the motions. - **Emotional flatness:** While I’m not feeling depressed, I don’t feel like my usual self either. - **Facial flushing:** My cheeks and nose often become hot and red, particularly after consuming certain foods or drinks; this reaction lasts for about an hour. - **Unintended weight loss:** This has raised some concerns for me, as it was not intentional. I also live with anxiety, which varies in intensity from day to day, yet I haven’t experienced full-blown panic attacks. Regarding medications, I take Vyvanse at 20mg occasionally and Xanax 0.25mg on an as-needed basis. In terms of family medical history, my mother suffers from several autoimmune disorders, prompting me to wonder if this could relate to my own health situation. I had recent blood tests, but my doctor dismissed my concerns. Despite this, I still feel off and want to determine the right steps going forward. The following lab results returned as abnormal: - **MCHC:** - Normal range: 32.0 - 36.0 g/dL - My value: 31.9 - (Low) - **Rheumatoid Factor:** - Normal value: <14 IU/mL - My value: <10 - **ANA Screen, IFA:** - Normal value: Negative - My value: Positive - **ANA Titer:** - My value: 1:40 - (High) - **ANA Pattern:** - My value: Nuclear, Speckled - (Abnormal) Has anyone experienced similar issues? Should I advocate for further tests or consult a specialist, perhaps an endocrinologist or rheumatologist? I appreciate any insights you might have.
Answers (1)

7/29/2025, 3:31:12 AM
OpenHealth AI
It sounds like you're experiencing a concerning combination of symptoms, including significant weight loss, fatigue, hair loss, easy bruising, cognitive issues, emotional changes, and facial flushing, along with abnormal lab results. These symptoms could suggest an underlying health issue that needs further exploration, especially given your family history of autoimmune disorders.
Explanation:
- Weight Loss and Fatigue: These can be signs of various conditions, including hormonal imbalances, autoimmune disorders, thyroid issues, or nutritional deficiencies.
- Hair Loss and Bruising: Increased hair loss and easy bruising can also indicate issues related to your immune system or deficiencies in certain vitamins and minerals.
- Cognitive and Emotional Changes: Feeling foggy and emotionally flat can be linked to physical health problems, mental health, or a combination of both.
- Abnormal Lab Results: The low MCHC and positive ANA (antinuclear antibody) test can be particularly relevant. A positive ANA could indicate autoimmune conditions, but it's not definitive on its own; further evaluation is typically required.
Next Steps:
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Document Symptoms: Keep a detailed diary of your symptoms, including when they occur and their severity. This can provide valuable information for your healthcare provider.
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Evaluate Diet and Nutrition: Ensure you're eating a balanced diet rich in vitamins and minerals. Consider including foods high in iron, vitamin D, B vitamins, and omega-3 fatty acids, which may support overall health.
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Consider Follow-up Testing: Advocate for further tests if needed, especially a complete blood count (CBC), thyroid function tests, and additional autoimmune markers to clarify the situation.
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Consult a Specialist: Given the complexity of your symptoms and lab results, it would be sensible to seek an appointment with a rheumatologist or an endocrinologist. They can provide more targeted evaluations for autoimmune disorders or endocrine issues.
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Manage Stress and Anxiety: Since you have anxiety, implementing stress-reducing techniques such as mindfulness, yoga, or counseling could also be beneficial.
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Follow Up with Your General Practitioner: If you're not feeling heard regarding your health concerns, consider seeking a new GP who will take your symptoms seriously and facilitate further testing.
It’s important to prioritize your health and ensure that you get the comprehensive care you need. If any of your symptoms worsen, seek immediate care. Remember, you’re not alone in this, and advocating for yourself is a crucial step in your health journey.
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