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Dealing with a Finger Sore While Immunocompromised

7/27/2025, 1:10:18 AMMale25-34

28-year-old female Diagnosed with Scleroderma Current medications: Enbrel injection, sulfasalazine, plaquenil As an individual with an autoimmune condition who is on multiple immunosuppressive therapies, my immune system is compromised. Over the past week, I've noticed an open wound on my finger that has progressively worsened. In the last day, I’ve developed some peculiar, painful bumps around the sore that feel unusually sensitive. Bending or straightening my finger has become difficult due to the discomfort. I visited my dermatologist yesterday, who performed a biopsy on one of the bumps. While they did not express any immediate concern, they were unable to provide a definitive diagnosis. About a week ago, I was prescribed mupirocin ointment, which I’ve been diligently applying and changing bandages regularly. My primary concern now centers around the sudden appearance of these bumps; they emerged unexpectedly two days ago and have significantly increased in size. Additionally, the sore itself is not showing signs of healing. Should I seek a second opinion, or is it typical for a sore to behave this way in someone with a compromised immune system? I have only been on Enbrel for a few months and have been keeping my rheumatologist informed, but they seem to be deferring to the dermatologist for further action.

ArthritisLupusRheumatology

Answers (1)

Cony

7/27/2025, 1:10:32 AM

OpenHealth AI

It’s understandable to be concerned about the open wound and the recent changes to your finger, especially given your immunocompromised state. Here are the key points to consider:

  1. Immune Considerations: With Scleroderma and the medications you’re on (immunosuppressants), your body may not respond to infections or injuries in the same way as someone with a fully functional immune system.

  2. Bump Growth and Pain: The unusual bumps and continued soreness could indicate infection or another complication that may need further evaluation. Although your dermatologist didn't express immediate concern, persistent symptoms merit attention.

Next Steps:

  1. Monitor Symptoms Closely: Keep an eye on the wound and the bumps. Look for signs of worsening, such as increase in redness, swelling, heat, or discharge. Note any changes in pain levels, particularly if it becomes more severe.

  2. Continued Use of Mupirocin: Continue applying the mupirocin ointment as prescribed. Ensure your bandages remain clean and dry, changing them regularly to aid healing and reduce infection risk.

  3. Pain Management: For discomfort, consider over-the-counter pain relief (like acetaminophen or ibuprofen), unless contraindicated by your personal health conditions or medications.

  4. Follow-Up with Healthcare Providers: Contact your dermatologist or rheumatologist and inform them about the rapid development of the bumps and lack of healing. Since you're immunocompromised, they may want to adjust your treatment or take further action based on your updated symptoms.

  5. Seek a Second Opinion if Necessary: If you feel your concerns are not being adequately addressed or if symptoms worsen, seeking a second opinion can be appropriate. Your health and comfort are paramount, and getting clarity about your condition is important.

In summary, stay vigilant about monitoring your condition, continue your current treatment, and don't hesitate to reach out to your healthcare providers to discuss your worries and any necessary adjustments to your care plan.

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