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Understanding Strongyloides IgG Antibodies

7/26/2025, 5:01:05 AMMale25-34

Hello everyone, I recently completed extensive blood tests and have been battling allergies since childhood. In addition to allergy testing, my allergist included several panels that assessed thyroid function, autoimmune diseases, and intriguingly, parasitic infections. Surprisingly, my test for IgG antibodies related to Strongyloides came back positive. Despite my knowledge, I have never experienced an infection nor undergone treatment for it. I haven't had any prior blood tests for parasitic infections, so I'm uncertain whether this antibody has been present for a long duration. Strangely enough, I reside in the United States, seldom travel abroad, and have not displayed any symptoms indicative of Strongyloides or similar parasitic or helminthic infections. Additionally, my lifestyle doesn't expose me to risk factors such as working with animals, going barefoot outdoors, or having encounters with fecal matter. The only possible exposure I can think of is having a dog during my childhood. I have a few questions: 1. How prevalent are false-positive results for this test? 2. Is there a risk of transmitting this to those around me, particularly to family members who are immunocompromised? 3. What are the possible ways I might have contracted this, and what implications does it hold for my health moving forward?

Drug AllergiesAsthmaAllergy & Immunology

Answers (1)

Cony

7/26/2025, 5:01:50 AM

OpenHealth AI

It's understandable to feel concerned upon receiving a positive test result for Strongyloides IgG antibodies, especially in the absence of symptoms or known exposure. Here’s an overview of your situation along with answers to your questions.

  1. False-Positive Results: False positives do happen with antibody tests, including those for Strongyloides. The rates vary, but in some studies, false positives can range from 5% to 20%, particularly in individuals with a history of allergies or autoimmune conditions. It’s important to discuss this result with your healthcare provider for potential confirmatory testing, like stool samples or more specific blood tests.

  2. Risk of Transmission: Strongyloides stercoralis is primarily transmitted through contact with contaminated soil and feces. In the case of immunocompromised individuals, the risk is higher if active infection occurs. However, since you have no symptoms and likely don’t have an active infection, the transmission risk to family members, including those who are immunocompromised, is low. Communicating with your healthcare provider about your family’s specific health concerns can help add clarity here.

  3. Possible Exposure and Health Implications: Potential pathways for contraction include contaminated water or soil, but if you haven’t experienced symptoms, there’s a possibility that this is a positive result from past exposure with no active disease. If you did have a past infection, your immune system could have controlled it without causing any symptoms. Your doctor may suggest follow-up testing to confirm whether there is a current infection or if monitoring is sufficient moving forward.

Next Steps:

  • Discuss Results: Schedule a follow-up with your allergist or primary care physician to talk about the positive antibody test and the possibility of confirmatory testing.
  • Symptom Monitoring: Keep an eye on your health for any new symptoms such as gastrointestinal issues, unexplained weight loss, or unusual skin changes. Report any such symptoms to your healthcare provider promptly.
  • Family Health Discussions: Talk with family members, especially those who are immunocompromised, about your situation for their peace of mind. It’s also a good time to review hygiene practices in home settings.

Remember, most individuals with positive IgG tests do not go on to develop active infections, especially if there are no symptoms present. You’re taking the right steps by seeking more information and guidance. Please don’t hesitate to reach out for further clarification or support as needed!

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