OpenHealth Q&A

Get answered by medical professionals

A Mistake I Made Regarding Serotonin Syndrome (19F)

7/26/2025, 4:50:22 PMMale25-34

I recently discontinued my 10mg dose of fluoxetine about two weeks ago. Not realizing the prolonged duration of the medication's effects in the system, I took 500mg of bromelain last night. Shortly after, I began experiencing some concerning symptoms, including an elevated temperature and an increased heart rate—peaking at 70 bpm, which is much higher than my normal rate of 40 bpm. These symptoms have somewhat intensified. Should I consider going to the emergency room for what seems to be a mild case of serotonin syndrome? Is there a possibility that my condition might deteriorate further?

Drug AllergiesHivesAllergy & Immunology

Answers (1)

Cony

7/26/2025, 4:50:41 PM

OpenHealth AI

It sounds like you're understandably concerned about your recent symptoms after stopping fluoxetine and taking bromelain. You're right to be cautious, as serotonin syndrome is a serious condition, but let's clarify a few points and outline some steps for you.

Main Points:

  1. Possible serotonin syndrome symptoms: Elevated temperature and increased heart rate can be concerning, particularly after changes to your medication regimen.
  2. Monitoring is key: Your symptoms should be taken seriously, especially since they have intensified.
  3. Emergency care: If your symptoms worsen, seeking immediate medical attention is crucial.

Explanation:

Serotonin syndrome can occur when there is an excess of serotonin in the brain, usually triggered by certain medications. Fluoxetine stays in your system for a while, and mixing it with other substances like bromelain could potentially lead to interactions.

The symptoms you've described—elevated temperature (fever) and an increased heart rate above normal—are consistent with serotonin syndrome, although elevated heart rates can also stem from various other causes. Your resting heart rate of 40 bpm is significantly lower than average, which could complicate your response to any changes in medication.

Next Steps:

  1. Monitor Symptoms Closely: Keep an eye on your temperature, heart rate, and any additional symptoms like restlessness, confusion, excessive sweating, or muscle rigidity.
  2. Stay Hydrated: Drink plenty of fluids to help your body manage any potential effects.
  3. Rest and Avoid Stimulants: Give your body time to recover, and avoid caffeine or other stimulants that could elevate your heart rate further.
  4. Emergency Care: If you experience severe symptoms (higher fever, severe heart rate increase beyond what you've reported, or if you feel very unwell overall), do not hesitate—go to the emergency room.

It’s always better to err on the side of caution when it comes to your health. Please keep monitoring yourself, and if things feel off, seek medical help promptly. Take care of yourself, and let me know how you’re doing.

Related Questions

Could This Be Eczema?

The subject in question is an 11-year-old boy who presents with a persistent itchy, red rash accompanied by inflammation and small bumps. Two pediatric specialists have diagnosed him with eczema. This condition seems to worsen during the winter months. In contrast, during the other seasons, the affected area appears rough and shows slight hyperpigmentation, but it remains free of redness and inflammation, and there are no symptoms during this time. Various treatments, including hydrocortisone, Duoderm, and Eucerin eczema lotion, have proven ineffective against the rash. For today, I have received a delivery from Amazon that includes Gold Bond medicated eczema relief lotion, white cotton gloves, and a non-soap hand cleanser. He is very particular about washing his hands after every restroom visit. I would appreciate your input and advice on whether I am on the right track with the treatment plan. Thank you for your assistance.

Skin AllergiesAllergy & ImmunologyDermatology
Male25-34
58 minutes ago

Is It Possible to Develop Allergies in Adulthood?

The concept of developing allergies later in life has been on my mind. A young woman I know, who is 22 years old, had no issues being near cats in her childhood. However, as she matured, she started exhibiting allergic reactions. Additionally, she used to enjoy strawberries without any problems, but recently she experienced swelling in her mouth after consuming a handful of them. To give you a bit of context, she stands at about 156 centimeters tall and weighs around 50 kilograms. It's noteworthy that she doesn't partake in alcohol, smoking, or any recreational drugs.

HivesAnaphylaxisPet Allergies
Male25-34
2 hours ago

Unexplained Urticaria Episodes

A 28-year-old woman, measuring 158 cm and weighing 72 kg, has been experiencing episodes of urticaria for the past month without any obvious cause. The issue began following a localized reaction to her migraine treatment, particularly the medication erenumab. Generally, she has minor reactions to this injection; however, the last two doses have led to significant flare-ups. Subsequently, she began to notice hives appearing sporadically, primarily without identifiable triggers. These episodes tend to intensify during the night but usually subside after taking cetirizine, an antihistamine. Additionally, she has known drug allergies to ciprofloxacin and penicillin. Recently, after taking cefpodoxime, she developed a rash within a few hours, although cefixime did not provoke any adverse reactions.

Drug AllergiesHivesAllergy & Immunology
Male25-34
2 hours ago

Concern Over Possible Botulism Exposure: Seeking Guidance

Greetings, everyone! I'm a 37-year-old male, weighing approximately 80 kilograms and standing at about 1.75 meters tall. To provide some context, I'm currently visiting a friend in another country, but I don’t have any travel health insurance. My friend had to work through the weekend and encouraged me to help myself to whatever food I found in her refrigerator. Upon arriving, I discovered some gravy that appeared and smelled fine. I decided to prepare some frozen fries in the oven while simultaneously heating the gravy in a dish, which I placed in the oven at a temperature of around 225 degrees Celsius. Following the instructions, I set a timer for 20 minutes when cooking the fries. However, when the timer went off, the fries didn’t seem fully cooked. I opted to give them an additional 10 to 15 minutes to bake (the gravy was still on the bottom, and I had completely forgotten about it). Eventually, the fries emerged from the oven, slightly overdone, but I didn't mind. Upon pulling everything out, I noticed that the gravy had begun to burn and char during the process. Afterward, I proceeded to eat the fries along with some of the gravy, which had turned into a paste-like consistency. I later called my friend to catch up and mention what I had for dinner. To my dismay, she panicked when I mentioned the gravy, informing me that it was actually 12 days old and stored in a plastic container. Now I’m left worried about my situation. How serious is this? To provide additional context: - It’s been 12 hours since I consumed the food, and I have not yet experienced any symptoms. What signs should I be vigilant for? - I heated the gravy thoroughly; it was in the oven for over 30 minutes, and the edges of the plate were charred. - Prior to this meal, I hadn't eaten anything for nearly 24 hours, so I'm hoping my stomach's acidity might be a protective factor. I didn't consume a large amount, discarding approximately half of what I had. I would greatly appreciate any advice or insights regarding this situation.

Hay FeverAnaphylaxisAllergy & Immunology
Male25-34
4 hours ago

Rash on the Dorsal Side of My Hands

A 24-year-old male, standing 5'3" and weighing 125 pounds, is not currently taking any medications. While I do not smoke, I am often exposed to secondhand smoke from those around me, and I have recently spent time in an environment where a significant amount of unpleasant smoke is produced due to casting activities. For approximately three weeks, I have been experiencing a rash on the backs of both my hands. I initially became aware of it after working on my car's engine. The rash has led to dryness and itching, and I took a photo after my shower today, highlighting the redness that has become particularly noticeable. What are some effective treatments for this condition?

Skin AllergiesAllergy & ImmunologyDermatology
Male25-34
9 hours ago