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Inquiry Regarding Medication Timing

7/18/2025, 12:20:21 AMMale25-34

I am a 33-year-old woman, measuring 5'4" and weighing 130 pounds. My current daily medications include Klonopin, Paxil, Zyrtec, Microgestin FE, as well as a Rephresh probiotic. Additionally, I take Ubrelvy 100mg as needed; for instance, I used it last night around midnight. I have recently been given a prescription for clotrimazole oral lozenges at a strength of 10mg, but I've noticed a warning indicating that these should not be taken alongside Ubrelvy. I am uncertain about the appropriate timing for starting the lozenges. Since it’s been approximately 17 hours since my last dose of Ubrelvy, would it be safe to begin taking the lozenges now? I am concerned about the potential side effects, which include elevated Ubrelvy levels in my body, along with increased drowsiness and nausea.

WellnessSupplementsInternal Medicine

Answers (1)

Cony

7/18/2025, 12:20:42 AM

OpenHealth AI

It's great that you're paying attention to your medications and potential interactions. Since you've been advised not to take clotrimazole lozenges with Ubrelvy due to possible interactions, it’s essential to be cautious and informed.

Key Points:

  • Ubrelvy (ubrogepant) is a medication for migraines, and it’s important to follow the caution against combining it with clotrimazole to avoid adverse effects.
  • Timing your medications correctly can help avoid these risks.

Explanation: The warning about not taking clotrimazole with Ubrelvy suggests there could be increased side effects, mainly due to higher levels of Ubrelvy in your system. Ubrelvy generally has a half-life of about 6 to 9 hours, meaning that after 17 hours, the levels in your body would be significantly lower, but they may not be completely cleared.

Next Steps:

  1. Waiting Period: Since it's been 17 hours since you took Ubrelvy, it's advisable to wait at least 24 hours after your last dose of Ubrelvy before starting the clotrimazole lozenges. This delay will help ensure that the effects of Ubrelvy are minimized.

  2. Monitor for Side Effects: When you do start the lozenges, monitor how you feel. Keep an eye out for increased drowsiness or nausea, and make sure you are in a safe setting when you start the medication.

  3. Hydration and Comfort: In the meantime, stay hydrated and rest as much as needed to help your body cope with whatever condition you're addressing with the clotrimazole.

If you have any unusual symptoms or continue to feel uncertain about the timing, consider discussing it with your pharmacist or healthcare provider for tailored advice.

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