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Considering the Possibility of Resuming Accutane After Elevation in Cholesterol and Triglycerides

7/11/2025, 11:30:31 AMMale25-34

Greetings, I am a 16-year-old male who has battled with acne for nearly four years. Throughout this period, I've tried various treatments, including tetracycline and doxycycline antibiotics, along with EpiDuo (a combination of adapalene and benzoyl peroxide) and topical retinoids like Treclin (tretinoin). Unfortunately, my acne has worsened instead of improving, which has adversely affected my self-esteem and mental well-being. In May, my dermatologist prescribed me Accutane for the first time. Before beginning the treatment, I underwent blood tests that showed no complications preventing me from using the medication. However, after four weeks on Accutane, my cholesterol and triglyceride levels spiked alarmingly high during a follow-up blood test. I was informed that my results were not just slightly elevated but extremely concerning. Consequently, I had to halt the Accutane treatment. I am scheduled for another blood test in two weeks, which will mark six weeks since I stopped taking the medication. I'm curious to know if there might be potential for me to resume Accutane. Could I possibly manage to take it alongside a statin to control my cholesterol and triglyceride levels? Thank you for your guidance.

Thyroid DisordersInternal MedicineEndocrinology

Answers (1)

Cony

7/11/2025, 11:30:56 AM

OpenHealth AI

It’s great that you’re reaching out about your experience with acne and your treatment options. It sounds like you've been through a lot, and it’s important to find an effective solution that also considers your overall health, especially regarding your cholesterol and triglyceride levels.

Main Points:

  • Accutane can effectively treat severe acne, but it may elevate cholesterol and triglycerides.
  • Monitoring lipid levels is crucial if considering a restart of Accutane.
  • Consult with your healthcare provider about lipid management options if resuming treatment.

Explanation: Isotretinoin (Accutane) is a powerful medication often used for severe acne when other treatments have failed. It can effectively reduce acne but does carry potential side effects, including increases in cholesterol and triglycerides. Since you experienced significant elevations that warranted stopping the medication, it’s crucial to approach the possibility of resuming treatment with caution.

As for the idea of taking a statin alongside Accutane, there are instances where doctors prescribe medications to manage cholesterol levels in patients on isotretinoin. However, this decision should be made with your healthcare provider, as they can evaluate your specific health profile, cholesterol levels, and the potential risks and benefits.

Next Steps:

  1. Monitor Blood Levels: Continue with your scheduled blood test in two weeks to assess your cholesterol and triglyceride levels. Share these results with your healthcare provider.

  2. Discuss Options with Your Doctor: After you get your results, schedule an appointment to discuss the possibility of resuming Accutane. Bring up your concerns about high cholesterol and ask about the potential use of statins or other options to manage your lipid levels while on Accutane.

  3. Consider Lifestyle Changes: While waiting, focus on a healthy lifestyle, including a balanced diet low in saturated fats and sugars, regular exercise, and managing stress, which can help improve cholesterol levels.

  4. Track Your Acne Progress: Keep a diary of your acne symptoms and any treatments you've tried, so you can have an informed discussion about the effectiveness of future treatments.

Remember, your healthcare provider is your best resource for managing both your acne and any concerns related to your cholesterol levels. You deserve a treatment plan that effectively addresses your acne while ensuring your overall health is prioritized.

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