OpenHealth Q&A

Get answered by medical professionals

Struggling with Persistent Non-Healing Wounds: Seeking Guidance

7/6/2025, 9:40:18 AMMale25-34

Hello everyone, I could really use your advice. My husband, who is 49, has been dealing with some health difficulties since approximately April 25. Initially, he had three bumps on his skin that seemed like boils or folliculitis. We attempted to treat them with antiseptic agents such as Hibiclens, peroxide, and alcohol, but they progressed into deep ulcers. On May 22, during the first appointment with his primary care physician (PCP), he was given a prescription for Doxycycline hyclate to be taken over seven days, but there was no improvement. By May 28, after a follow-up visit, he was prescribed Mupirocin for a duration of ten days, yet again, this did not yield any results. On June 10, during the third consultation, a culture test was performed, and he was started on Doxycycline monohydrate twice daily for ten days, along with Keflex for the same period; unfortunately, there were still no changes. The culture test didn’t reveal any significant findings. The fourth visit occurred on June 19, where two additional tests were done. He was then prescribed Amoxicillin-clavulanate for ten days and referred to a dermatologist for further examination. Results from a fungal infection lab reported nothing conclusive, but the "Deep Non-Healing Wound" panel indicated the presence of Peptostreptococcus anaerobius, Peptoniphilus asaccharolyticus, Finegoldia magna, and Anaerococcus prevotii. He had an appointment with the dermatologist on June 25, but she expressed uncertainty about the diagnosis and recommended applying Polysporin. This treatment has not been effective, and she scheduled a follow-up for a biopsy. Given her lack of confidence in managing the case, we are hesitant to return for further consultation. As of today, he has completed five days on Metronidazole with no sign of improvement. The ulcers continue to ooze and cause him significant pain. We are feeling overwhelmed and are running out of options. Any suggestions or advice would be greatly appreciated. Thank you. 😢

ArthritisLupusCOPD

Answers (1)

Cony

7/6/2025, 9:40:35 AM

OpenHealth AI

I'm truly sorry to hear about the struggles your husband is facing with these persistent non-healing wounds. It's understandable to feel overwhelmed when treatments seem ineffective. Here’s a summary of the situation and some actionable steps you can consider moving forward.

Summary of Key Points

  • Your husband has had non-healing ulcers that have persisted despite multiple antibiotic treatments and a thorough evaluation.
  • Recent tests identified specific anaerobic bacteria, indicating that the infections may be complex and not responding to standard treatment.
  • Current topical treatments, like Polysporin, haven't provided relief.

Explanation

Non-healing wounds can result from various factors, including underlying health conditions, infections (especially with resistant bacteria), or the wound environment itself. It's crucial to address any potential contributing factors that might hinder healing, such as blood sugar levels in diabetes, circulation issues, or nutrient deficiencies. Given the presence of specific bacteria in the culture, the challenge could also be in selecting the right antibiotic that effectively targets these organisms.

Next Steps

  1. Focus on Wound Care:

    • Keep the wounds clean and covered with an appropriate dressing to promote a moist environment, which can enhance healing. Consider using hydrocolloid or alginate dressings, which may be more effective than standard bandages.
    • If there is significant oozing, ensure that the dressings are changed regularly to prevent maceration and further infection.
  2. Nutritional Support:

    • Ensure your husband is consuming a nutrient-rich diet with adequate protein, vitamins (especially Vitamin C and D), and minerals (like zinc), as these are vital for wound healing.
    • If dietary intake is a concern, consider discussing a multivitamin or specific supplements to support healing.
  3. Pain Management:

    • For discomfort, over-the-counter pain relievers like ibuprofen or acetaminophen can help alleviate pain while facilitating daily activities. Ensure it's taken as advised on the label or consult with a pharmacist for appropriate dosing.
  4. Explore Further Testing:

    • Since the dermatologist suggested a biopsy, it may provide deeper insights into the underlying cause of non-healing. Biopsy results can help tailor treatment options more effectively.
    • It may be worthwhile to see if a wound care specialist or infectious disease expert can offer additional insights or alternative therapies.
  5. Follow-Up:

    • Schedule the follow-up with the dermatologist or seek a second opinion from another dermatologist or wound care specialist if you feel the current treatment approach is not yielding results.
    • You could inquire about options like negative pressure wound therapy or other specialized treatments that may be warranted based on the biopsy results.

Reassurance

I understand how this situation has been stressful for both of you. Continuing to advocate for your husband's health is essential, and there is help available that can lead to improvements. Maintain communication with healthcare professionals, and don’t hesitate to voice your concerns during appointments. You are not alone in navigating this, and it's good to seek support during such challenging times.

Related Questions

Neurological Challenges Mimicking POTS Symptoms

A 36-year-old female, weighing 265 pounds, is dealing with a complex medical history that includes conditions like Complex Regional Pain Syndrome (CRPS), bipolar disorder, anxiety, PTSD, and a splenic artery aneurysm. There is a tentative diagnosis of hypertensive Postural Orthostatic Tachycardia Syndrome (POTS). The patient experiences significant symptoms when not on medication, including a rapid heartbeat (ranging from 117 to 150 beats per minute), dangerously high blood pressure, episodes of vision impairment, difficulty walking accompanied by stumbling and falls, tremors, memory issues, and brain fog. Currently, her medication regimen includes Pristiq, lithium, lorazepam, low-dose naltrexone for pain management, and propranolol to regulate heart rates. She takes ubrelvy when needed. In January, a recurrence of severe pain radiating from her right side led to a hospital admission where her gallbladder was surgically removed due to complications. Although the surgery was successful, she subsequently developed CRPS, further complicating her health. While working in the emergency department, she experienced a sharp tearing pain associated with her known aneurysm. Unable to manage the pain, she informed her manager of her need to leave. During her walk back to her workspace, approximately 1500 feet away, she began to stagger and lost her vision, while also experiencing heavy sweating and shortness of breath. Support from coworkers was crucial, as she lost her strength and collapsed, gasping for air and experiencing vertigo. Her heart rate was recorded at almost 150 bpm and her blood pressure at 152/120. Once lying down, her vitals stabilized but would escalate again with movement. The attending nurse suspected POTS based on her symptoms. Despite efforts to provide explanations, her overnight doctor attributed her condition to anxiety. However, subsequent doctors recognized her situation increasingly suggested POTS and put her on a heart monitor after she began falling to one side, which later confirmed episodes of tachycardia over a monitoring period of two to three days. Her first cardiology appointment revealed a drop in her blood pressure when she stood, further aligning with the POTS suspicion. An echocardiogram was scheduled for the following week, but complications arose the very next morning at work, where rising distress prompted coworkers to assist her following an apparent episode of tachycardia. Administered Ativan temporarily helped alleviate some symptoms, but as her condition worsened, she was transported to the emergency department once again. After several hours of treatment, she was discharged with little clarity regarding her condition. Currently, she takes an extended-release dose of propranolol (80 mg), but without it, her heart rate can exceed 130 bpm, accompanied by memory lapses. Episodes of sporadic vision loss persist, alongside difficulty walking that has progressed to staggering or being unable to move at all, leading to falls. These occurrences are thought to be related to syncope. Neurological evaluations are underway, with initial tests like ECG and EEG returning normal results, but an MRI suggested increased intracranial pressure, though some specialists doubt its relevance. A pain specialist indicated that her pain conditions may not directly correlate but suggested central nervous system dysfunction related to stress could be a factor, as her symptoms often intensify during anxious moments. An Ear, Nose, and Throat specialist found no abnormalities causing her symptoms, and her cardiologist is pursuing further investigation at a specialized clinic, expressing concern about her ongoing employment due to the physical and financial strain it entails. The patient’s aneurysm was treated with an embolism in September, adding another layer to her intricate medical profile, and she is seeking additional perspectives on her challenging situation.

HypertensionMultiple SclerosisCOPD
Male25-34
6 minutes ago

Understanding Prolapsed Appendix in Young Adults

Hello all, I’m a 25-year-old woman who has been struggling with persistent abdominal discomfort, along with nausea and diarrhea, for more than a decade. A recent colonoscopy has diagnosed me with a prolapsed appendix, despite the fact that my colon appears unaffected. Biopsy samples were collected to investigate potential inflammation, and I am currently awaiting those results. Additionally, I have a balloon enteroscopy scheduled to examine my small intestine more closely. From my research, it seems that appendiceal prolapse or intussusception is quite uncommon in adults. I am particularly interested in understanding how rare this issue truly is, especially for someone at my age, along with the typical causes that could lead to this condition. I have a few queries: How uncommon is a prolapsed appendix in adult patients? What are the most frequent causes linked to young women like myself? Are there specific risk factors or trends that might increase the likelihood of developing this issue? I’m not seeking a personal assessment, but I would be grateful for any information from those who are familiar with the occurrence and causes of this condition.

Crohn's DiseaseCOPDInternal Medicine
Male25-34
6 minutes ago

Unusual Urges to Consume Non-Food Items

At 23 years old, I am contending with various health issues, including anemia (with an iron saturation of 6%), and I’ve read that this might be influencing my bizarre cravings. There’s more going on with my health, but delving into all of it would take quite a while. Recently, I stumbled upon a video showcasing cleaning techniques, and I experienced an intense and unexpected hunger when I witnessed the soap lathering. Despite having dinner afterward, my cravings persisted, and regular food has proven ineffective at satisfying my appetite. To provide some background, I also have bipolar II disorder, ADHD, OCD, PTSD, and generalized anxiety disorder. These peculiar cravings appeared following several stressful experiences in my life. In the past, I was compelled to induce vomiting due to an OCD ritual, which I believed was linked to avoiding “bad luck.” Logically, I understood that there was no connection, but at one point, I was so entangled in these thoughts that I restricted my food intake entirely, convinced that eating brought misfortune. I was also unmedicated during that challenging period. Fortunately, I managed to break those cycles a few years ago, but now I face an ongoing struggle with overwhelming hunger. I find myself in the obese category today, unlike previously, and I am actively pursuing options for gastric bypass surgery due to my incessant appetite. Although I feel confident I won’t actually consume soap, I am concerned that sharing these cravings might jeopardize my chances of qualifying for the procedure. Still, if there’s a viable solution, I’d like to discover it. These cravings don’t dominate my thoughts, yet whenever I come across soap—either in videos or in person—I get this overwhelming desire to consume it. It’s as if I believe that succumbing to this urge would somehow provide relief and satisfaction. I’ve made a conscious effort to limit my viewing of such cleaning videos but find myself tempted to order edible chalk to see if that might alleviate my unusual hunger.

ArthritisFibromyalgiaCrohn's Disease
Male25-34
16 minutes ago

Did I Experience a Seizure Upon Waking?

This morning, I had an awakening that was unlike anything I’ve felt before. As a 23-year-old man, I’m familiar with sleep paralysis, often waking up immobile; however, today was distinct. I found myself in a state that resembled paralysis but accompanied by rapid, shallow breaths, akin to hyperventilation—something I don’t typically experience, even during strenuous activities. My body was trembling, reminiscent of numbness from cold or perhaps involuntary contractions throughout. Additionally, I felt a strange pressure on my groin, coupled with discomfort in my right testicle, as if they were being retracted into my body. I don’t regularly take medication aside from using an albuterol inhaler during asthma flare-ups. Standing at 6 feet 4 inches tall and weighing approximately 210 pounds, I also had a particularly unsettling dream just prior to waking, which might explain my reaction (at least, I hope it does). However, I can’t shake the anxiety that this could have been a type of seizure and I’m eager for input from those who have more expertise on the subject.

AsthmaCOPDInternal Medicine
Male25-34
16 minutes ago

Are My Symptoms Indicating an Impending Stroke?

I’m a young adult female, weighing 99 pounds and standing 5 feet 2 inches tall. I do not smoke, vape, or consume alcohol, and currently, I am undergoing tests for POTS and HEDS. For the past two weeks, I have been experiencing intermittent discomfort in the upper region of my head, particularly in the back and temples. These aren’t typical headaches, but rather sudden twinges of pain that occur sporadically throughout the day. Additionally, over this same period, I have been dealing with bouts of vertigo—probably about 4 to 5 days where it came and went. A few days back, I also encountered a tingling sensation in my arms, which I can’t tell if it was simply due to anxiety. Given that my aunt suffered a stroke in her thirties, the prospect of having a stroke terrifies me. I find that the emergency room here primarily prescribes pain medication if you mention head discomfort, which leaves me uncertain about what steps to take next. Could these symptoms signal an impending stroke? Furthermore, I've also been experiencing pain in my left leg, though I’m unsure if that’s connected to my other symptoms.

LupusCrohn's DiseaseCOPD
Male25-34
46 minutes ago