36-Year-Old Male from West Texas Seeking Answers for Multi-Systemic Symptoms Since 2018
Hello, I am a 36-year-old man residing in West Texas, and I am reaching out for insights from medical experts or those with relevant knowledge. Since engaging in a sexual encounter in 2018, I have experienced an array of complex, debilitating symptoms impacting various bodily systems—specifically neurological, vascular, immune, and renal. Despite extensive testing and consultations with numerous specialists, a definitive diagnosis has eluded me. --- **Primary Symptoms:** - **Neurological Issues:** I have been dealing with muscle spasticity, tremors, fatigue, cognitive challenges, disruptions in speech, emotional fluctuations, and a decrease in cognitive processing speed. Additionally, I am facing visual issues such as double vision, distorted sight, and misalignment in eye coordination (binocular dysfunction). Tinnitus and concentration difficulties are also prevalent. - **Vascular Concerns:** I have been diagnosed with venous reflux and peripheral venous disease. An imaging study (IVUS) indicated the presence of four non-functioning veins in my right leg and three in my left. Circulation has markedly diminished, with an 87% reduction on the left and 54% on the right. Despite the physician’s mention of “significant disease,” no underlying cause has been determined, and while stents and blood thinners have been suggested, I have not proceeded with those treatments yet. - **Renal Symptoms:** I experience kidney discomfort, detect protein in my urine, and notice heightened uric acid levels. - **Immune and Inflammatory Responses:** My CRP levels remain persistently elevated (up to 17), and blood tests show irregular results, including raised MCH%, Eosinophils (EO%), and Lymphocytes (LY%), along with low Neutrophils (NEU%) and Mean Platelet Volume (MPV). - **Other Issues:** I face central sleep apnea, shortness of breath, popping joints (particularly in my knees), burning sensations in my legs, an unusual temperature perception in my feet, and elevated blood pressure. Symptoms tend to exacerbate post-sexual activity, with some minor relief brought by ibuprofen, whereas caffeine and sodium can worsen my condition. --- **Medical Assessments:** - I have undergone MRI scans (both with and without contrast) and an EEG, all of which returned normal results. - A blood test for Myasthenia Gravis yielded negative results. - I was referred to two rheumatology specialists, both of whom found no autoimmune triggers. - Currently, I am not using blood thinners or stents. - One neurologist suggested that my symptoms might be anxiety-related, yet they delved no further, and I have been prescribed antidepressants, which I believe do not address the root of my issues. --- **An Odd Connection:** Interestingly, my dog exhibited remarkably similar symptoms prior to passing away: seizures, tremors, disorientation, aggressive behavior, fungal infections, gastrointestinal problems, and a ruptured gallbladder. This resemblance has led me to speculate on a possible environmental or zoonotic origin for my condition. --- **Questions I Have:** 1. Could this be a long-standing, undiagnosed infection (viral, bacterial, or fungal) influencing multiple body systems? 2. What might account for the vascular deterioration observed with no identifiable cause? 3. Are there uncommon immune or systemic disorders that could manifest this combination of neurological, vascular, renal, and immune symptoms? 4. What type of specialist or diagnostic pathway should I consider (such as infectious disease, immunology, hematology, or neurovascular)? 5. Is it possible that I am experiencing effects from toxic exposure, chronic inflammation, or an unusual systemic condition? I have felt brushed off by several physicians who attribute my situation to mere “stress,” but I am convinced that there is an underlying issue that needs attention. Any insights or thoughts—whether conventional or alternative—would be immensely valued. Thank you for your time.
Answers (1)
6/25/2025, 11:50:53 PM
OpenHealth AI
Thank you for sharing the details of your situation. It sounds incredibly challenging, and it's understandable to feel frustrated when facing such complex symptoms without a clear diagnosis. Let's address your questions while considering your symptoms and experiences.
Main Points:
- Potential Undiagnosed Infection: Your symptoms suggest the possibility of a hidden infection affecting multiple systems.
- Vascular Deterioration Causes: Various factors might contribute to vascular issues, needing further exploration.
- Uncommon Disorders: Consider systemic conditions that affect the nervous, vascular, renal, and immune systems.
- Specialist Referral: Explore specialized pathways to uncover undiagnosed conditions.
- Toxic Exposure/Chronic Inflammation: Chronic exposure and persistent inflammation can play roles in systemic health problems.
Explanation:
Your collection of symptoms—neurological changes, vascular issues, and signs of renal dysfunction—can arise from several complex conditions, including infections, autoimmune disorders, or even toxin exposure. Although tests have ruled out many conditions, further investigation is necessary since symptoms continue without a diagnosis.
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Long-standing infections (like Lyme disease or mycoplasma) may not always show up correctly on initial tests. Chronic infections can lead to multi-system inflammation, which might explain elevated CRP and other symptoms.
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Vascular deterioration could result from multiple factors, including past infections, genetic predispositions, or environmental factors. The reduced circulation raises concern for vascular health that warrants more investigation into the underlying causes or risk factors.
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Uncommon conditions: There are several rare disorders (e.g., systemic vasculitis, Ehlers-Danlos syndrome, or connective tissue diseases) that could present similarly to your symptoms.
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Diagnostic Pathway: Consider consulting with:
- Infectious Disease Specialist for advanced testing and screening for chronic infections, including tick-borne diseases.
- Immunologist to evaluate for potential rare immune disorders.
- Hematologist to understand your blood parameters and if they relate to vascular health.
- Neurovascular Specialist for insights into the neurological aspects and vascular health.
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Toxic exposures and chronic inflammation: Reflect on environmental factors, potential exposure to toxins, or chronic stressors that could be affecting your health. Discussing these with a specialist could lead to further insights.
Next Steps:
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Keep a Detailed Symptom Journal: Record your symptoms daily, including flares after specific activities or exposures, to share with specialists.
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Consult with Specialized Doctors: Start reaching out to specialists mentioned to investigate potential underlying issues.
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Evaluate Environmental Factors: Consider an environmental assessment in your home or workplace for potential exposure to harmful substances.
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Follow up on Comprehensive Labs: Request more comprehensive testing for latent infections, autoimmune markers, and systemic inflammation if not already done.
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Communicate Concerns: When you meet with specialists, express your desire for a thorough investigation rather than general assessments. Don't hesitate to seek second opinions if you feel your concerns are not being addressed adequately.
Conclusion:
Navigating through numerous symptoms without diagnosis is frustrating but continuing to seek answers is essential. Prioritize your health by pursuing avenues that address all the layers of your symptoms. I'm here to provide support and guidance as you navigate this challenging journey.
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