Post-Hiking Biochemical Analysis: CK, CK MB, LDH, and Aldolase Levels
A 35-year-old male weighing 64 kg and standing at 167 cm completed a moderately intense hike covering 20 km, with the first blood draw occurring 45 hours post-activity and the subsequent test taken 66 hours after the excursion. Here’s a recap of the relevant lab results: 📊 CK Levels: - 42 hours post-hike: 3039 U/L (reference value: <174 U/L) - 66 hours post-hike: 3080 U/L (reference value: <174 U/L) 📊 CK-MB Level: - 66 hours post-hike: 56 U/L (reference value: <24 U/L) 📊 LDH Levels: - 42 hours post-hike: 337 U/L (reference value: <247 U/L) - 66 hours post-hike: 380 U/L (reference value: <247 U/L) 📊 Aldolase Level: - 20 U/L (normal value: <7.6 U/L) Further analyses: - CRP and ESR were reported within normal limits. - Physical symptoms noted were only mild muscle soreness, with no signs of weakness, and overall good health was reported. This raises a question: are these results common for someone just starting out? I consulted with my doctor today, who indicated that this situation does not warrant concern. Nonetheless, my tendency to have health-related anxieties left me feeling unsettled, especially in light of my elevated CK levels. Additionally, I recalled an incident from four years ago when a random Anti-Jo-1 result was indicated through an Immunoblot test, although I exhibited no symptoms at that time. Follow-up testing via FEIA later confirmed negative results, and the original test was conducted for an entirely different purpose. Since then, I’ve remained vigilant regarding my CK levels and their implications.
Answers (1)

6/25/2025, 3:50:44 PM
OpenHealth AI
It's understandable to feel anxious about elevated CK levels, especially after engaging in a physically demanding activity like hiking. Your lab results show significantly elevated levels of creatine kinase (CK), CK-MB, LDH, and aldolase, which can all stem from intense physical exertion. Here’s a closer look at your results and actionable next steps.
Summary of Your Lab Results:
- CK Levels: Your CK levels (3039 U/L and 3080 U/L) are very high, indicating muscle damage or stress, which is common after strenuous exercise, particularly for those who may be new to such activities.
- CK-MB Levels: The elevated CK-MB (56 U/L) may suggest muscle injury, as this enzyme is often associated with heart muscle damage but can also rise in skeletal muscle injury.
- LDH and Aldolase Levels: Both LDH and aldolase levels are also elevated, further pointing towards muscle strain or damage.
Explanation:
These elevated levels are not unusual following an intense exercise session, especially if you are not accustomed to such activities. Muscles can release these enzymes into the bloodstream during strenuous workouts as they undergo repair and recovery processes. The absence of severe symptoms (like significant weakness or pain) and normal inflammatory markers (CRP, ESR) support that this is likely a temporary response to your hike rather than a sign of a serious condition.
Next Steps:
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Rest and Recovery:
- Allow your body time to recover. Avoid strenuous physical activity for several days to help your muscles heal.
- Focus on gentle movements or low-intensity exercises to keep blood flowing without straining your muscles.
-
Hydration and Nutrition:
- Stay well-hydrated; water helps flush out toxins and supports muscle recovery.
- Ensure your diet includes adequate protein and nutrients that support muscle repair (e.g., lean meats, fish, legumes, nuts, fruits, and vegetables).
-
Monitor Symptoms:
- Keep track of any gradual changes in your muscles and overall health. If you notice new, concerning symptoms like severe pain, swelling, or persistent fatigue, consider following up.
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Follow-Up Testing:
- Discuss with your healthcare provider the possibility of re-testing CK levels in a few days or a week to monitor any downward trends, which can help reassure your mind regarding your recovery.
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Manage Anxiety:
- If health-related concerns are causing significant anxiety, consider speaking with a mental health professional or engaging in relaxation techniques such as mindfulness or meditation.
Overall, while your lab results are notable, they reflect a response to physical exertion rather than a chronic health issue, especially given the slight muscle soreness and normal inflammatory markers. Keep communicating with your doctor about your worries—they can provide tailored advice and reassurance. Let me know if you need more information on any of these points!
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