Seeking Advice on Recurring UTIs
I'm a 31-year-old woman who has never experienced recurrent urinary tract infections (UTIs) until recently. I'm in a committed marriage and have only had sexual relations with my husband. In February, I was diagnosed with Hidradenitis Suppurativa (HS) and prescribed a low dose of Doxycycline to be taken over 90 days. After completing the treatment in early May, I unfortunately developed a UTI. A urine culture confirmed the presence of bacteria, and I was given Cefpodoxime. While it eased the symptoms, it didn’t completely eradicate the infection. Ten days later, I returned for a follow-up, and my urine culture returned positive again, now showing a different strain of bacteria. This prompted my treatment to switch to Cephalexin, which was more effective, but symptoms resumed almost immediately after I finished the course. I went back for a third urine culture at Urgent Care, which came back positive yet again, identifying yet another type of bacteria. This time I received Nitrofurantoin. It provided some symptom relief, but similar to before, it didn’t permanently clear the infection. Fast forward to last week, when I went to the emergency room. The doctor performed a pelvic examination along with tests for bacterial vaginosis, yeast infections, trichomoniasis, and STDs, all of which returned negative results. They also cultured my urine for the fourth time, which again confirmed a UTI, this time caused by the same bacteria identified in the second infection. I was then administered a dose of antibiotics via injection and started a four-week course of low-dose Cephalexin. A week into this regimen, I still experience mild symptoms. Out of concern, I conducted an over-the-counter dip test, which indicated the presence of leukocytes, leading me to believe that I might still have a lingering infection. Some additional points to consider: - I have refrained from sexual activity for three weeks now. - I am cutting back on caffeine. - I’m taking a double dose of probiotics daily, along with cranberry supplements and D Mannose. What could be causing this ongoing issue, and why can't I seem to overcome it? I feel overwhelmed and am seeking any insights into what I might be missing. I’m trying to schedule an appointment with a urologist, but they are booked solid for months, and I’m currently awaiting a referral. I would greatly appreciate any help or advice on how to proceed.
Answers (1)

6/25/2025, 3:50:42 AM
OpenHealth AI
I'm sorry to hear that you've been experiencing such persistent UTIs. This situation can be incredibly frustrating and concerning. It sounds like you've already taken some proactive steps. Let's break down the potential reasons for your unresolved infections and explore some actionable steps you can take while awaiting your urologist appointment.
Main Points:
- Recurrent UTIs can occur due to various factors, including anatomical issues, hormonal changes, and changes in gut flora.
- Your current regimen is commendable, but there may be additional lifestyle or dietary changes worth exploring.
Explanation:
Recurring UTIs can arise from several underlying causes, including:
- Anatomical factors: Certain anatomical features can contribute to increased susceptibility to UTIs.
- Hormonal influences: Hormonal changes can affect the urinary tract and lead to infections.
- Gut and vaginal flora imbalance: Antibiotics can disrupt your natural flora, leading to further infections. Probiotics are beneficial, but timing and specific strains matter.
- Patient fact: You mentioned a history with Hidradenitis Suppurativa and antibiotics; this can alter your microbiome, potentially making you more vulnerable to UTIs.
While your regimen of probiotics, cranberry supplements, and D Mannose is great, additional steps can also aid in prevention and management.
Next Steps:
- Continue your current regimen: Maintain the probiotics and cranberry supplements but ensure they are high-quality products known for effectiveness.
- Hydration: Increase your fluid intake if you haven't already; aim for at least 8-10 cups of water daily to help flush your urinary system.
- Dietary modifications:
- Limit sugar and processed foods, as they can promote bacterial growth.
- Consider adding garlic and onion to your meals, as they have natural antibacterial properties.
- Hygiene practices: After using the restroom, wipe from front to back. Consider urinating right after sexual activity to help clear any bacteria.
- Monitor symptoms: Keep a detailed record of your symptoms, dietary habits, and any additional changes. This can be helpful for the urologist when you do have an appointment.
- Explore other causes: If symptoms persist, consider asking about testing for other potential underlying conditions, such as pelvic floor dysfunction or interstitial cystitis, which can mimic UTI symptoms.
- Use over-the-counter options: An over-the-counter urinary analgesic can help relieve discomfort temporarily while you work toward a longer-term solution.
I hope these suggestions help you find relief and clarity. You're taking all the right steps, and it's important to stay proactive while waiting for specialized care. If you encounter any alarming symptoms, such as fever, chills, severe abdominal pain, or vomiting, please seek immediate care. Please let me know if you need more specific advice or support!
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