Concerns About Lymph Node Tuberculosis Progression
Greetings. Four months ago, a relative of mine, a 58-year-old female, began experiencing some discomfort and mild pain in the lower right side of her neck. In response, we sought medical attention at the hospital, where a surgeon recommended a series of diagnostic tests, including X-rays, CT scans, and blood tests. Among these tests was a Mantoux test, which confirmed exposure to the tuberculosis (TB) bacterium. The imaging results revealed a cyst forming in the lower neck area. Subsequently, we conducted both FNAC and TruCut biopsies on the lump, and fortunately, the findings indicated no signs of malignancy. This entire process unfolded over approximately a month, during which she developed a persistent low-grade fever and significant fatigue. After further evaluations, the surgeon raised the possibility of TB and instructed us to consult a pulmonologist. The pulmonologist later diagnosed her with Tuberculosis Lymphadenitis. Although none of the biopsies had definitively confirmed the TB infection at that time, we commenced her treatment with a regimen of Anti-TB medications including Isoniazid, Rifampicin, Ethambutol, and Pyrazinamide. She has been on this treatment for more than 1.5 months; however, there has been no sign of improvement. In fact, the cyst has increased in size and hardness, and she continues to experience daily fevers. Just a week ago, her condition worsened, leading to a diagnosis of an infection. The pulmonologist added a new set of antibiotics to her treatment regimen. Unfortunately, her body seems to be unresponsive to these antibiotics. She has lost her appetite, shed some weight, and feels constantly fatigued despite taking dietary supplements. Currently, she has been readmitted to the hospital. The attending physician suspects that the pus from the cyst may be the source of her infection, and she is undergoing a CT scan. The doctor mentioned that surgery might be a necessary next step. I am reaching out for advice from medical professionals on this platform, particularly regarding whether she should seek a second opinion. I feel very stressed and uncertain about the situation. If medical recommendations aren't possible, I would appreciate any words of encouragement or hope. Note: Initially, the surgeon was reluctant to proceed with surgery due to the cyst's proximity to vital arteries, which posed risks of complications. He had anticipated that the TB treatment would help mitigate the cyst’s influence.
Answers (1)

6/25/2025, 7:30:53 AM
OpenHealth AI
I'm really sorry to hear about your relative's struggles with Tuberculosis Lymphadenitis and the complications she's facing. It’s understandable to feel stressed in such a challenging situation. Let’s break down the key points and focus on some constructive next steps.
Main Points:
- Your relative is undergoing treatment for TB lymphadenitis but the treatment has not shown improvement.
- There’s concern regarding an infection associated with the cyst that may require surgical intervention.
- Seeking a second opinion could be beneficial to reassess her treatment plan and overall management.
Explanation: TB lymphadenitis can be complex to treat, and the presence of a cyst that has not responded to medical therapy indicates that further evaluation and possibly more aggressive treatment may be necessary. Tuberculosis can sometimes be difficult to manage, particularly if there are complications or secondary infections. It's good that she has a team of specialists involved, and her readmission to the hospital reflects the seriousness of her condition.
Next Steps:
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Consider Seeking a Second Opinion: Especially since she hasn't improved after 1.5 months of TB treatment and has developed further complications. A second opinion can provide fresh insights and might help in deciding on the necessity for surgery or adjustments in her treatment.
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Communicate with Her Healthcare Team: Encourage open dialogue with her doctors regarding her condition, treatment efficacy, and the symptoms she’s experiencing, including appetite loss and persistent fever. This can ensure that the team is aware of her current health status and may prompt a reassessment of her treatment plan.
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Ask About Surgical Options: If the cyst is suspected to be the source of ongoing infection, surgical intervention may become necessary. Discuss the potential benefits and risks of surgery with her healthcare providers.
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Supportive Care: Ensure she stays hydrated and eats small, nutritious meals that she can tolerate. This can help in supporting her overall strength during treatment. Managing fatigue with adequate rest is important, as is mental health support for both her and the family.
Empathy & Reassurance: It's completely natural to feel overwhelmed in this situation. It's important to remember that medical professionals are there to help your relative, and seeking additional opinions is a common practice when dealing with complex health issues. You’re taking proactive steps by gathering information and support, which is commendable. Stay hopeful, and encourage your relative to focus on her recovery with the support of her healthcare team and loved ones. If you need further information or reassurance, please feel free to reach out again.
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