Unusual Mark on Thigh: Seeking Answers
I am a 31-year-old female, standing at 5 feet 4 inches tall and weighing 135 pounds. I identify as Caucasian and reside in South Carolina, USA. For the past couple of months, I have been noticing a peculiar spot on the front of my upper thigh. It doesn’t cause any itching or discomfort, but it’s visually concerning. Initially, my doctor suggested it might be ringworm, and I followed their advice, applying the prescribed ointment for over eight weeks. Unfortunately, it did not show any improvement and has even expanded in size. Now, I am starting to wonder if it could be something like Lyme disease, given that mosquitoes, in addition to ticks, can transmit it. Living in the South, I’m accustomed to encountering plenty of mosquitoes. I’m contemplating whether I should seek the expertise of a dermatologist for a biopsy or another form of evaluation. This situation is increasingly frustrating, especially with the summer season in full swing, as I feel self-conscious about wearing a bathing suit. I am eager to find a solution and prevent this from getting worse.
Answers (1)

6/24/2025, 9:20:46 PM
OpenHealth AI
It’s understandable to feel concerned about an unusual mark on your thigh, especially since you’ve already sought treatment without improvement. Let’s break down the situation and outline some actionable steps for you.
Main Points
- An unusual spot that hasn’t responded to treatment for ringworm may need further evaluation to identify its cause.
- Lyme disease primarily results from tick bites rather than mosquito bites, and the mark on your thigh could be related to several other conditions.
- Consulting a dermatologist is a strong next step to properly assess the mark.
Explanation
You mentioned that the spot on your thigh has been present for a couple of months and has not improved with the antifungal treatment suggested for ringworm. Since it has also increased in size, this is a valid reason for concern. Conditions to consider include dermatitis, an allergic reaction, psoriasis, or other skin conditions, rather than just ringworm or Lyme disease.
Lyme disease is transmitted through ticks, not mosquitoes. If you had a known tick bite and develop a rash in a specific pattern, that may increase suspicion, but given the context, it’s not the most likely cause for your thigh mark.
Next Steps
- Consult a Dermatologist: Schedule an appointment with a dermatologist to get a professional evaluation of the mark. They may perform a biopsy or other tests to clarify what the lesion is.
- Document Changes: Keep a record of any changes in the spot’s appearance, including size, color, or texture. Take pictures for reference if it’s necessary to examine it over time.
- Avoid Irritation: While waiting for your dermatologist appointment, try to keep the area clean and avoid any irritants like heavy creams or sprays, which might worsen the condition.
Taking these steps can help you get closer to a diagnosis and appropriate treatment. Remember, it’s perfectly normal to feel uneasy about something like this, and you’re being proactive by seeking answers. Keep me updated on how it goes!
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