Exploring the Potential Systemic Effects of Steroid Injections
A 14-year-old male patient has undergone a series of three steroid injections using DEPO-MEDROL, aimed at treating a keloid scar measuring two inches located on his knee. These injections were administered over a span of four months, with intervals of two months separating each treatment. The dosages for the injections were as follows: the first dose was 40mg, the second was 12mg, and the third was 8mg. Given this treatment regimen, questions arise regarding its safety profile, particularly concerning potential effects on growth. Is there a risk that such steroid use could hinder normal development? Thank you for your insights.
Answers (1)

6/21/2025, 5:30:44 AM
OpenHealth AI
The use of steroid injections such as DEPO-MEDROL can provide effective treatment for keloid scars, but there are valid concerns regarding their safety and potential effects on a growing adolescent's development.
Main Points:
- Effects on Growth: Concerns exist that systemic corticosteroids may impact growth and development in adolescents.
- Dosage Considerations: The doses and frequency of administration are important to assessment.
- Monitoring and Next Steps: Observe for any side effects and consider long-term health.
Explanation:
Corticosteroids like DEPO-MEDROL can influence growth by potentially suppressing the adrenal glands, especially when used in higher doses or over extended periods. For a 14-year-old, whose body is still developing, significant exposure to systemic steroids could theoretically lead to growth suppression if not managed properly. However, the doses you mentioned (40mg, 12mg, and 8mg) are relatively low, particularly when spread out over several months. While local injections can have less systemic impact, individual responses can vary.
Next Steps:
- Monitor Growth: Keep an eye on growth patterns and general health. Check for any changes in height, weight, and overall development over the coming months.
- Watch for Side Effects: Be alert for symptoms such as increased appetite, mood changes, or any unusual physical manifestations. These could signal systemic effects of the steroid.
- Maintain Communication: Keep open lines of communication with the prescribing physician. If there are any concerns regarding growth or side effects, discuss these with them for potential adjustments in treatment.
- Consider Alternatives: If worries about growth persist, ask about alternative treatments for keloids that may have fewer systemic effects, such as silicone gel sheeting or laser therapy.
In summary, while the growth impact from these steroid injections can be a concern, careful monitoring and communication with your healthcare provider will help manage risks and ensure the best outcomes for your child's health. If you have further questions or need clarification on specific symptoms, feel free to reach out!
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