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Could My Inhaler Have Caused Hives?

6/20/2025, 9:10:27 PMMale25-34

As temperatures rise in Chicago, my asthma symptoms have flared up. For context, I am 62 years old, 5 feet 8 inches tall, and weigh 203 pounds, leading an active lifestyle. I’m currently on Wegovy and thyroid medications for Hashimoto’s disease, specifically Levothyroxine and Liothyronine, without any complications. Additionally, I use Trazodone to help with sleep issues and Escitalopram to manage anxiety. Earlier today, I mistakenly used an expired inhaler, specifically Albuterol Sulfate HFA Inhalation Aerosol by TEVA, with an expiration date of March 2022. My asthma is generally mild, which is why I hadn’t refilled my prescription yet. About 45 minutes after using the expired inhaler, I noticed hives appearing on both my upper arms. I’m wondering if there’s a connection between the two. To address the hives, I took a dose of Benadryl and while their appearance has diminished, they resembled small mosquito bites. I won’t be using that expired inhaler again, but I’m curious if inhalers can indeed trigger hives. It might be time to consider switching brands. I’d appreciate any insights on this matter. My asthma troubles began later in life, especially after I gained some weight, and it tends to act up under conditions of extreme heat or poor air quality. Over the past two years, I've been steadily losing weight and have yet to engage in much activity today. Thank you for any suggestions or advice you can share!

AsthmaArthritisThyroid Disorders

Answers (1)

Cony

6/20/2025, 9:10:42 PM

OpenHealth AI

It’s understandable to be concerned about the connection between using an expired inhaler and the development of hives. While expired medications may lose potency, they typically do not cause allergic reactions. Here’s what we know about your situation:

Main Points:

  1. Hives might not be directly caused by the expired inhaler.
  2. Allergic reactions can occur from various sources, including medications or environmental factors.
  3. Taking Benadryl was a good immediate response to the hives.

Explanation:

Expired medications, including inhalers like Albuterol, usually do not become harmful, but they may become less effective. The appearance of hives (which can look like small mosquito bites) is often linked to allergic reactions or irritation. Factors such as heat, humidity, or even stress can contribute to flare-ups of both hives and asthma symptoms.

Given your active management of asthma and existing medications, it's also possible that something in your environment or lifestyle—rather than the inhaler—could have triggered the reaction.

Prioritized Next Steps:

  1. Monitor Your Symptoms: Keep an eye on the hives and any associated symptoms. Check if they return or if you experience any other changes.
  2. Avoid Expired Medications: Do not use any expired inhalers or medications in the future. Ensure to refill your prescription for Albuterol to maintain access to effective treatment.
  3. Track Recent Changes: Consider if you've introduced any new products (like lotions, soaps, or foods) that might cause irritation or allergic reactions.
  4. Maintain an Allergy Diary: Note any changes in your environment or activities leading up to your symptoms to help identify potential triggers.
  5. Stay Hydrated and Cool: Keep your body cool in warm weather to manage asthma symptoms and lessen skin reactions. Hydration can also help your skin.

If the hives persist, worsen, or if you experience additional symptoms such as difficulty breathing or swelling, please take action to seek care promptly. Your health and comfort are important, and it’s always good to ensure a proactive approach to asthma management and skin reactions. Let me know if you need further details or assistance!

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