Can Adapalene Increase Dizziness? Considerations While Freezing Eggs
32 years old, female, weighing 70 kg and standing 170 cm, previously a smoker. I have been diagnosed with POTS and manage my symptoms effectively through Ivabradine and Midodrine. Recently, I’ve noticed an increase in dizziness and severe cold sweats. I want to explore whether these might be linked to my use of adapalene (in conjunction with benzoyl peroxide), as it has been a significant concern for me. While some online sources suggest dizziness could be a side effect, they mainly associate it with allergic reactions. Here are alternative reasons for my worsening dizziness that I am also considering: - The brand of Midodrine I usually use has been out of stock for a month, forcing me to get it compounded. - Additionally, I am recovering from a debilitating flare-up of a sacroiliac injury, which has prevented me from walking to the train station for work. Consequently, I haven’t been as active lately, leading to a decrease in my physical conditioning, which is frustrating. I’m truly fed up with dealing with this condition. All I want is to feel normal again. **Related note:** Adapalene has been effective for managing the severe cystic acne I developed after having my Mirena removed. I am also about to start the process of freezing my eggs. Could the use of adapalene negatively impact my future embryos? I’ve gone through the effort of quitting smoking to avoid harming my potential future children with a topical acne treatment. Moreover, I’ve been advised to wait three months between quitting smoking and egg retrieval. Is it necessary to apply the same waiting period for retinoids? Thank you all for your input!
Answers (1)
4/3/2025, 11:50:39 AM
OpenHealth AI
It's understandable that you're feeling concerned about the increase in dizziness and cold sweats you’ve been experiencing, especially as you're managing a condition like POTS and preparing for egg freezing. Let's break down your questions about adapalene and its potential effects, as well as your concerns about egg freezing.
Main Points:
- Dizziness and Adapalene: While dizziness is not commonly listed as a side effect of adapalene, individual reactions can vary. Other factors likely contribute, such as medication changes and decreased physical activity.
- Impact on Fertility and Future Embryos: Adapalene, as a topical retinoid, is generally considered safe for pregnancy and fertility when used externally. However, it's wise to consult with your fertility specialist for personalized guidance.
- Waiting Period after Quitting Smoking: Similar to smoking cessation, it's advisable to maintain a waiting period for certain medications, including retinoids, but this timeframe can vary based on individual factors.
Explanation:
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Dizziness: Adapalene itself is unlikely to be the primary cause of your dizziness. The recent change in your Midodrine formulation, fluctuations in your physical activity, and possibly even your recent sacroiliac injury can also play significant roles in your symptoms. It's essential to monitor your symptoms closely and consider if reduced activity or medication changes coincide with your increasing dizziness.
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Adapalene and Future Embryos: Retinoids, including adapalene, are absorbed very minimally through the skin and are not known to significantly affect fetal development. Studies generally indicate topical retinoids are considered safe during conception attempts, but it’s always best to discuss your specific concerns with a reproductive specialist.
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Waiting Period Considerations: After quitting smoking, a three-month waiting period is recommended to improve fertility outcomes. While retinoids do not have a standard waiting guideline like smoking, it's prudent to discuss with your doctor whether to stop using topical retinoids before proceeding with egg retrieval.
Next Steps:
- Monitor Symptoms: Keep a diary of your dizziness, noting any triggers or changes in medication and activity levels. This can help identify patterns and adjustments you can make.
- Stay Active: As much as your injury allows, try to incorporate gentle physical activity (like stretching or walking) into your routine to help with overall health and POTS symptoms.
- Discuss with Professionals: Reach out to your healthcare team, including your dermatologist and fertility specialist, to review the safety of your current treatments and any necessary adjustments. Bring your concerns about dizziness and medication changes to their attention.
Feel free to ask more questions, and take care of yourself as you navigate these challenges!
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