Reaction to HRT Injection - Two Weeks In
I'm an 18-year-old FTM, usually in good health. About two weeks ago, I administered my first testosterone injection as a trans male. The dosage was 100mg/ml of Testosterone Cypionate, and I used a 31-gauge, 5/8-inch needle for a subcutaneous injection at a 45-degree angle on my outer thigh. Initially, I didn't experience any pain when injecting, and I took my time while ensuring the area was properly sanitized. Everything seemed fine at first; however, after about three to four days, I noticed a hard lump forming under the skin, accompanied by some bruising in the same area. To avoid aggravating it, I refrained from applying any pressure and treated it with warmth and compression. Unfortunately, the situation worsened. The lump has become increasingly painful, and there's a bit of itchiness as well. Thankfully, I'm not experiencing any fever, hives, or discharge from the lump. Despite this, the hardness in the area remains, and after cautiously administering my second injection, I’ve noticed a repeat occurrence of the same issues. Mobility has become challenging, but applying ice provides some relief. I’m seeking advice on what I should do next. Is there a specific term for this condition, and what could be the underlying cause?
Answers (1)
3/20/2025, 9:10:37 PM
OpenHealth AI
It sounds like you are experiencing a common reaction to subcutaneous testosterone injections, which could be related to localized irritation or a reaction at the injection site. It’s important to address your discomfort and ensure you’re managing this properly.
Explanation
The hard lump, bruising, and increased pain you're experiencing may be due to a few factors, including:
- Injection Site Reaction: This can occur due to irritation from the hormone or the needle used for injection.
- Hematoma: A bruise that forms as blood leaks into the tissues, often resulting from blood vessels being nicked during the injection.
- Lipodystrophy: A condition where the fatty tissue under the skin changes, which can cause lumps where injections are frequently given.
The itchiness you mentioned might suggest some degree of inflammation, possibly from the body reacting to the testosterone or from the injection itself.
Next Steps
Here are some prioritized steps you can take to manage the situation:
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Continue using Ice: Since ice has provided some relief, continue to apply it intermittently (15-20 minutes at a time) to reduce swelling and pain.
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Pain Management: Consider over-the-counter pain relievers like ibuprofen (if you don’t have any contraindications) to help with the pain and inflammation.
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Avoid injecting in the same area: Try rotating injection sites to prevent further irritation or tissue changes in the affected area.
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Monitor Symptoms: Keep an eye on the lump and any changes. Note if the pain increases, or if new symptoms arise (such as fever or pus).
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Gentle Massage: If the area isn't too painful, gently massaging the lump might help to disperse the fluid and encourage healing.
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Follow-Up Care: If the lump does not improve in a week or worsens further, or if you experience any new symptoms, it’s important to consult with a healthcare provider for further evaluation and management.
Reassurance
This type of reaction, while uncomfortable, is often manageable and can improve with the right care practices. Remember, it’s always best to consult with a healthcare provider for personalized advice and if you feel uncertain about your symptoms.
If you have further questions or need more specific advice, feel free to ask!
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