Ensuring Effective Sedation for My Upcoming Gastrointestinal Procedure
I am a 21-year-old female, weighing 90 kg and measuring 161 cm, with an important gastroscopy scheduled to collect biopsies from my esophagus. I have been experiencing several gastrointestinal problems. Last year, during a previous gastroscopy where only a local anesthetic was used, the doctors diagnosed me with esophagitis, gastritis, Barrett's esophagus, and noted a significant laxity at the gastroesophageal junction. Unfortunately, the procedure was not well tolerated, and they were unable to secure any biopsies. This is why I will be undergoing twilight sedation, which includes fentanyl and midazolam, for the upcoming procedure. Despite this planned sedation, I am nervous because I previously tried twilight sedation during a colonoscopy, and it proved ineffective for me. Given the traumatic experience of my last gastroscopy, I am understandably anxious. My concern is that if the sedation failed back then, what are the chances that it will work this time? I am currently using medical cannabis and cocodamol (15/500) to manage my hypermobile Ehlers-Danlos syndrome. Would it be beneficial for me to take these medications before the procedure, and would I need to inform the medical team? Additionally, I am curious about why the sedation may have been ineffective in the past and what strategies I could employ to increase the chances of successful sedation this time around. Also, if the doctors once again find it impossible to retrieve biopsies, what alternative options would be available to me? Regarding my ongoing treatment, I am taking famotidine at a dosage of 20 mg and esomeprazole at 40 mg.
Answers (1)
2/14/2026, 7:50:38 PM
OpenHealth AI
It's completely understandable to feel anxious about your upcoming procedure, especially given your previous experiences. The concern about sedation effectiveness is valid, and I'm here to help you navigate this.
Main Points:
- Sedation Effectiveness: Twilight sedation may work differently for each procedure. Past experiences can influence future outcomes.
- Medication Disclosure: Informing your medical team about your current medications is essential, particularly regarding cannabis and cocodamol.
- Alternatives if Biopsies Are Not Obtained: Discuss possibilities with your doctor if the procedure does not achieve the desired results.
Explanation:
Sedation Effectiveness: Twilight sedation combines medications to help you feel relaxed and pain-free. Factors like your body's unique response to the sedatives, anxiety levels, and the type of procedure can affect how well sedation works. If you had a tough time with twilight sedation before, it's helpful to share this with your healthcare team, as they might adjust their approach.
Medication Disclosure: Always inform your medical team about all medications you're taking, including cannabis and cocodamol. They can assess potential interactions and might alter your sedative plan based on your current medications.
Prioritized Next Steps:
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Communicate with Your Medical Team: Before the procedure, ensure you discuss your previous sedation experience and current medications with the healthcare provider. This could help modify the sedation plan to improve effectiveness.
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Manage Anxiety: Consider discussing anti-anxiety medication options with your doctor. Techniques such as deep breathing exercises or guided imagery might also be beneficial before and during the procedure.
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Ask About Alternative Approaches: If biopsies cannot be retrieved during the procedure again, ask your doctor about other diagnostic options. These could include imaging studies or other types of endoscopic procedures later.
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Prepare Logistically: Ensure that someone is available to bring you home post-procedure due to the sedation effects. Also, rest adequately before the day of the procedure.
Remember, your medical team wants to make your procedure as comfortable and effective as possible. You're taking important steps by preparing and asking the right questions. If you have more questions or need further clarification, don’t hesitate to ask!
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