Does Systemic Nickel Allergy Syndrome Relate to Lupus?
Greetings everyone! I’m very new to this, having just learned from my recent emergency room visit that I have a significant allergy to nickel, which was highlighted in my records. Currently, I'm dealing with a rash on my face that resembles a butterfly rash, alongside swollen glands. In a Facebook group focused on Systemic Nickel Allergy Syndrome (SNAS), I’ve noticed others also reporting similar rashes and gland swelling. I was prescribed Zyrtec, which I can take up to three times daily. After just one day of use, I already sense a change; this morning, my glands are a bit swollen again but not as severely as before. I’m about to take my morning dose of Zyrtec, and I have an appointment with my primary care physician later today. Years ago, I received a blood transfusion due to low iron levels, which was complicated by the difficulty in finding a compatible match because my blood showed a "Lupus marker." The medical staff reassured me not to be concerned and sent me home post-transfusion. I hadn’t thought much about it until experiencing the swollen glands and butterfly rash recently. I’m really frightened and feel lost in all of this. I’ve visited the emergency room twice over the past three weeks, and it’s been nearly life-threatening. I wish to avoid a long, drawn-out process with doctors circling back on the same issues if I can help it. Typically, I don’t fall ill, but whenever I do, it turns into something intense. At the time of my transfusion, I had bilateral pulmonary embolism, and that’s when they first mentioned the lupus marker. I was treated with Eliquis and birth control for a year to manage heavy periods but stopped taking Eliquis while continuing the birth control until about two months ago. At this moment, I’m dealing with heavy bleeding while typing this out. If anyone has suggestions on what specific tests I could ask my doctors for, it would mean a lot. My family and I are feeling very overwhelmed, and I’m struggling to cope with the idea of being lost in this situation for an extended period.
Answers (1)
2/13/2026, 5:50:41 PM
OpenHealth AI
You're experiencing a complex situation with your systemic nickel allergy syndrome (SNAS), potential lupus markers, and concerning symptoms like the butterfly rash and swollen glands. It's understandable to feel overwhelmed, especially after multiple emergency visits and the challenges with your health.
Main Points
- Connection Between SNAS and Lupus: While there isn’t a direct connection between systemic nickel allergy syndrome (SNAS) and lupus, both can lead to similar symptoms like rashes and inflammation. It’s important to investigate these thoroughly.
- Current Symptoms: Your butterfly rash and swollen glands are concerning, especially in the context of lupus markers and past health issues. Monitoring and managing these symptoms is essential.
- Next Steps for Testing and Management: You can guide your healthcare provider towards specific tests to clarify your situation and help manage your symptoms.
Explanation
Systemic Nickel Allergy Syndrome (SNAS) occurs in individuals who are allergic to nickel, which can cause skin-related symptoms, including rashes. A butterfly rash can be indicative of lupus, but having a lupus marker doesn’t mean you have lupus; it suggests you may be at higher risk or have other related autoimmune issues.
Your symptoms of swollen glands, rash, and heavy bleeding need to be addressed holistically. The fact that you are feeling better with Zyrtec is a good sign, but it doesn’t tackle the root causes of your symptoms.
Actionable Next Steps
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Discuss Specific Tests with Your Doctor:
- Autoimmune Panel: Request tests for antibodies commonly associated with lupus, such as Antinuclear Antibody (ANA) and anti-dsDNA antibodies. These can help clarify your autoimmune status.
- Complete Blood Count (CBC): This can provide essential information about your blood and immune system, especially in the context of your heavy bleeding.
- Lymph Node Evaluation: Given your swollen glands, consider discussing imaging studies (like an ultrasound) if they're significant or persistent.
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Symptom Management:
- Continue taking Zyrtec as directed and observe any changes. Track your symptoms, noting anything that worsens or improves.
- For heavy bleeding, discuss with your doctor the possibility of adjusting your birth control or exploring other management options.
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Informed Questions for Your Doctor:
- Ask about the implications of your lupus marker and what next steps look like if lupus is confirmed.
- Inquire whether an allergist’s consultation may be beneficial for managing SNAS more effectively.
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Emotional Support:
- Consider seeking support groups or counseling. The emotional burden of dealing with potential chronic conditions can be heavy. Reaching out to others facing similar challenges could help provide comfort and strategies.
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Plan for Doctor Visits: Make a list of your symptoms, concerns, and questions to create a focused approach during your appointments. This ensures you cover all your points without feeling rushed.
You're not alone in this, and your responses to medications and tests can guide your next steps towards better health. Continue advocating for yourself and gather as much information as you can during your healthcare visits.
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