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Seeking Guidance on Urine Sample for Chronic UTI Referral

2/12/2026, 11:30:24 PMMale25-34

Hello everyone! I'm reaching out for some advice from this knowledgeable community. I've been battling chronic urinary tract infections (UTIs) since I started being sexually active at the age of 18, experiencing an infection roughly once a month. Following the birth of my first child through a cesarean section, during which I had a catheter, the frequency of these infections decreased significantly to about every two or three months. During this period, I was given a medication called Microdantin to take at the onset of symptoms, which generally worked well, allowing me to avoid a full course of antibiotics on most occasions. Fast forward over a decade, and I find myself entering perimenopause. I've been on hormone replacement therapy (HRT) for around four months, and it has been incredibly beneficial for various symptoms. However, alongside these positive changes, I've unfortunately experienced a spike in UTIs, with an average of one infection per week over the past four months. My doctor prescribed nitrofurantoin 50mg daily, but I had to raise the dosage to 100mg as the lower amount wasn't effective enough. The 100mg seems to be working, and I've even discovered that I can enjoy a glass of wine if I take my medication earlier than usual. I recently underwent an ultrasound that came back clear, prompting a referral to a urologist. However, they have now requested an active urine sample, which both my general practitioner and I suspect indicates they are looking for a current infection. Last night, I indulged in two glasses of red wine, and as expected, I started feeling that familiar uncomfortable pressure and tingling sensation that precedes an infection. I thought I might not make it through the night, so I took a double dose of Ural and a sleeping pill. To my surprise, I felt somewhat better in the morning—not completely symptom-free, but not in full-blown infection mode either. Now, I have a question that might seem a bit trivial. I collected a urine sample with my first morning pee, knowing this often has the highest concentration for testing. Should I hold on to that sample or wait to see if a full infection develops and then collect another? I'm really anxious about the prospect of submitting a negative sample after enduring so much discomfort. Is it permissible to submit multiple samples for testing? For context, I’m based in Australia and my referral is associated with Laverty. Thanks in advance for your support!

BronchitisAllergy & ImmunologyPulmonology

Answers (1)

Cony

2/12/2026, 11:30:44 PM

OpenHealth AI

It's understandable to feel anxious about submitting a urine sample, especially after experiencing such discomfort from recurrent UTIs. Here's a clear breakdown of your situation and what to do next.

Main Points:

  1. Urine Sampling for UTI Testing: You can submit the urine sample you've already collected, as it is a good representation for testing.
  2. Monitoring Symptoms: Since you are experiencing symptoms resembling a UTI, it's important to keep track of these to inform your healthcare provider.
  3. Submitting Multiple Samples: Generally, you can submit more than one sample if needed, but check with your lab to confirm their policies.

Explanation:

The first morning urine sample is typically the most concentrated and can be very valuable for testing for a UTI. Since you're already feeling some discomfort, this sample can help capture any potential infection. If you develop more significant symptoms later, you might consider a second sample to confirm ongoing issues.

Given your history of chronic UTIs and the current situation, it is also completely valid to express your concerns about potentially providing a negative sample after dealing with recurrent issues.

Next Steps:

  1. Submit the Current Sample: Go ahead and submit the urine sample you've collected. It should provide useful information.
  2. Monitor Symptoms: Keep an eye on any changes in your symptoms. If your discomfort worsens, consider taking additional self-care measures, such as staying well-hydrated and avoiding irritants (like alcohol or caffeine) that may exacerbate your symptoms.
  3. Prepare for Your Urologist Appointment: Document your symptoms, their timing, and any triggers, along with the effectiveness of your medications. This information can be tremendously beneficial for your urologist to understand your situation better.
  4. Confirm Sample Policies: Check with Laverty or your doctor if it's possible and acceptable to submit another sample later, particularly if your symptoms escalate or change significantly.

Your health and comfort are paramount. It's great that you're being proactive about managing this recurring issue, and I wish you the best as you navigate this situation. If you have further questions or concerns as you await your appointment, feel free to reach out.

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