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Inquiry About Proctitis Treatment

2/12/2026, 1:50:25 AMMale25-34

I'm a 37-year-old male, standing at 5'5", currently undergoing treatment with mesalamine 1000 mg in suppository form. I was recently diagnosed with proctitis a few weeks back. Since starting the mesalamine, my bleeding has ceased, which is certainly a positive development. However, I've noticed that some days my condition seems to worsen, accompanied by symptoms such as brain fog and abdominal discomfort. Should I continue with the mesalamine for another month despite these fluctuations, or is there a risk that the bleeding could return if I discontinue too soon?

ArthritisLupusCrohn's Disease

Answers (1)

Cony

2/12/2026, 1:52:48 AM

OpenHealth AI

It's great to hear that your bleeding has stopped since starting mesalamine, as this is a positive sign of improvement. However, your ongoing symptoms like brain fog and abdominal discomfort are important to address, as fluctuations in symptoms can be distressing.

Explanation

Proctitis can indeed be a complex condition, and mesalamine is commonly prescribed to reduce inflammation in the rectal area. Stopping your medication prematurely may lead to a return of symptoms, including bleeding. It's crucial to give the treatment time to work fully, typically several weeks, and your provider may suggest continuing it for a full course.

The brain fog and abdominal discomfort could be side effects of mesalamine or may relate to your proctitis itself. Monitoring these symptoms is essential because they can impact your overall well-being.

Next Steps

  1. Continue Mesalamine: Stick with the mesalamine for now, especially since you’ve seen an improvement in bleeding. Consistency can be key to managing proctitis effectively.

  2. Monitor Symptoms: Keep a daily log of your symptoms, noting any patterns or triggers related to the brain fog and abdominal discomfort. This may help identify if there are specific foods or activities exacerbating these issues.

  3. Hydration and Diet: Ensure you are well-hydrated and consider a diet low in irritants (like spicy foods, caffeine, and high-fiber foods temporarily) to see if it helps with the abdominal discomfort.

  4. Self-Care: Engage in activities that can help alleviate brain fog, such as regular light exercise, mindfulness, or short walks. They can enhance your overall mood and cognitive function.

  5. Follow-Up: While it’s not mentioned, a follow-up appointment with your healthcare provider may be beneficial to reassess your treatment plan, especially if symptoms persist.

If your symptoms significantly worsen or if bleeding returns, please consider an urgent review of your treatment plan. Remember, you're not alone in managing this condition, and it's important to seek support when needed.

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