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Navigating an Uncertainty: Seeking Clarity on Health Struggles

2/11/2026, 5:50:39 PMMale25-34

I have a lot of information to share, and I want to ensure you grasp every detail! **A bit about myself**: I’m a 29-year-old female, carrying around 10 extra pounds. This situation began unexpectedly around February 2024. I rarely drink—perhaps once a year—and I do not smoke. Occasionally, I consume a low-dose edible, but there can be months where I don’t partake at all. **Medical background**: I have been diagnosed with several conditions including gastroesophageal reflux disease (GERD), hypothyroidism, type 2 diabetes (which is managed), mixed hyperlipidemia, polycystic ovary syndrome (PCOS), non-alcoholic steatohepatitis (NASH), tachycardia, anxiety, bipolar disorder type II, and autism. **Current medications**: My medication regime consists of *Rybelsus* 3mg, *Nikki*, *Rosuvastatin Calcium* 5mg, *Levothyroxine* 50mg, *Voquezna* 20mg, *Spironolactone* 25mg in the morning and evening, *Lamictal* 150mg twice a day, *Propranolol* 20mg taken day and night, *Trintellix* 20mg, along with *Hydroxyzine* and *Zofran* as needed. I have just recently begun taking Rybelsus. **Gastrointestinal concerns**: - I experience persistent nausea and rely on medication daily to manage it. - I have episodes of vomiting, often occurring at night. I can predict the onset, as I shake, my nose runs, I get goosebumps, feel the urge to use the restroom (though I never actually do), and then I vomit repeatedly until all that’s left is bile. This can happen almost daily, or as infrequently as a few times per month. - Nearly everything I consume causes discomfort in my stomach. - I infrequently have regular bowel movements. **Dermatological issues**: - I suffer from intense itching that seems to spike 1-2 times a month, typically lasting around five days. During these episodes, I scratch to the point of pain. - My tattoos and scars often appear raised and bumpy. - Symptoms tend to escalate when I’m unwell or after a hot shower or bath. - Such reactions can also occur without clear triggers. **Other health challenges**: - I am continually fatigued, and my energy diminishes even further when I go out. Engaging in activities for a single day can leave me bedridden for a week. Simple tasks feel overwhelmingly taxing. - I struggle with generalized body pain; sitting at my desk for extended periods is painful. - I frequently feel weak. - Most of my days are spent feeling dizzy, with many instances of stumbling due to lightheadedness. - The pain is particularly acute in my legs. - I find it difficult to stay warm. - Daily heart palpitations are a common occurrence. - My nails, especially my toenails, are extremely fragile and tend to break easily. **Medical evaluations undertaken**: I’ve undergone multiple endoscopies, cortisol tests, MRIs of my brain, CT scans with and without contrast, regular blood tests, celiac disease screenings, a gastric emptying study, and a swallow test. I consult a primary care physician who appears perplexed and somewhat unmotivated, along with a gastroenterologist who has referred me to a prominent hospital as she feels uncertain about how to proceed. **Additional notes**: I have experimented with medication adjustments—trying to cease, reduce, or switch them—as well as different diets. My weight has fluctuated between a little overweight and a healthy range; the onset of my symptoms wasn’t triggered by any medication or lifestyle change. I have used a continuous glucose monitor (CGM) with no notable link to my blood sugar levels, and I receive annual ultrasounds for my thyroid. This situation has profoundly affected my daily life, often confining me to bed due to fatigue or illness. I’ve faced several emergency room visits owing to dehydration, and I have previously tried three other GLP-1 medications that exacerbated my issues. Additionally, I had my gallbladder removed in 2019.

Thyroid DisordersEndocrinologyRheumatology

Answers (1)

Cony

2/11/2026, 5:51:06 PM

OpenHealth AI

Key Points: You've reported numerous interconnected health challenges that are significantly impacting your daily life. Common issues include persistent nausea and vomiting, intense itching, fatigue, dizziness, heart palpitations, and body pain. Addressing these concerns requires a structured approach to manage symptoms and improve your quality of life.

Explanation:

You have complex medical conditions, including GERD, hypothyroidism, PCOS, diabetes, and NASH, and you're on a comprehensive medication regimen. Your symptoms like nausea, vomiting, and fatigue can stem from these conditions or may be related to medication side effects or interactions. Furthermore, the severe itching and dermatological reactions may indicate an underlying condition, potentially aggravated by your other health issues.

Next Steps:

  1. Symptom Diary: Start keeping a detailed diary of your daily symptoms. Note what you eat, medications taken, the intensity of your symptoms, and any triggers. This will help you and your healthcare providers identify patterns and potentially problematic areas.

  2. Dietary Adjustments:

    • Try smaller, more frequent meals to help reduce nausea and GERD symptoms.
    • Focus on a well-balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Consider foods that are less likely to trigger your reflux, such as bananas, oatmeal, and lean meats.
  3. Hydration & Nutrition: Given your episodes of dehydration from vomiting, prioritize hydration. Consider electrolyte-rich beverages to maintain balance. If nausea persists, smaller sips of water, herbal teas, or broths might be soothing.

  4. Medication Review: Since you've experienced varying effects from your GLP-1 medications, it may be wise to revisit your full medication regimen with your primary care physician or a pharmacist to evaluate potential interactions or side effects contributing to your symptoms.

  5. Fatigue Management: Introduce gentle, restorative activities like stretching, yoga, or walking. Gradually increase your activity levels as tolerated to help build stamina without overwhelming your body.

  6. Dermatological Care: For intense itching, consider soothing topical treatments, such as hypoallergenic moisturizers or anti-itch creams (e.g., those containing hydrocortisone) to alleviate symptoms. Discuss alternatives with your dermatologist, especially if you notice raised, bumpy skin on your tattoos and scars.

  7. Regular Monitoring: Keep up with your scheduled follow-ups, including lab tests for your thyroid and blood sugar levels, as oversight in these areas can further impact your health.

  8. Support System: Connecting with patient support groups for chronic conditions can provide you emotional support and practical management strategies from others facing similar challenges.

Take these actionable steps one at a time, adapting based on your body's response. Communicate openly with your healthcare providers about any changes or worsening symptoms. You are navigating a complex situation, but these systematic adjustments can help provide clarity and enhance your overall well-being.

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