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Are There Lasting Effects from Long-Term Use of Montelukast?

2/8/2026, 1:20:14 AMMale25-34

Hello everyone! To provide some background, I was prescribed montelukast at a young age—around 4 or 5 years old—continuing until I was about 10 or 11. During that time, I experienced significant levels of aggression. Unfortunately, none of the medical professionals we consulted suggested discontinuing the medication or indicated that my symptoms could have been related to its use. This has left me with some unresolved feelings so I’d rather not delve deeper into that right now. Currently, it has been some time since I stopped taking montelukast, but I find myself grappling with certain challenges. While I’m hesitant to elaborate unless absolutely necessary, I’m curious whether anyone knows about potential long-term side effects from prolonged use of this medication during childhood. Thank you so much for your insights! Much appreciated! <3

AgingFamily MedicinePreventive Medicine

Answers (1)

Cony

2/8/2026, 1:20:25 AM

OpenHealth AI

It's understandable to have concerns about the long-term effects of medications like montelukast, especially given your early experiences. Montelukast is primarily used to manage asthma and seasonal allergies by blocking certain chemicals in the body that cause inflammation.

Main Points:

  1. Potential Long-Term Effects: Some studies have suggested that long-term use of montelukast may be associated with neuropsychiatric events, such as mood changes or aggression, particularly in children.
  2. Current Symptoms: If you're experiencing ongoing challenges, it's important to address these directly, regardless of whether they relate to montelukast.

Explanation:

Montelukast, while effective for managing asthma and allergies, has been linked to various side effects, including behavioral changes, especially in young users. Although research is ongoing and conclusions vary, it is acknowledged that some individuals may experience side effects that persist even after stopping the medication. This could be related to changes in neurochemistry, environmental factors, or underlying conditions.

Next Steps:

  1. Monitor Your Current Challenges: Reflect on any remaining issues you’re facing. Write down specific symptoms and when they occur.
  2. Practice Self-Care: Engage in activities that consider your mental well-being, such as regular exercise, maintaining a healthy diet, and practicing mindfulness or relaxation techniques to alleviate any stress or anxiety.
  3. Seek Support: If you're comfortable, consider talking to a mental health professional about your experiences and any unresolved feelings. They can provide strategies to cope with lingering symptoms that may affect your daily life.
  4. Stay Informed: Keep yourself updated on any new research related to montelukast and its effects; this may help you understand your situation better.

Your feelings are valid, and taking proactive steps is always beneficial. If you have specific symptoms or concerns you'd like to explore further, I'm here to help.

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