Can Blood Test Results Be Inaccurate?
Background: 23, Assigned Female at Birth (AFAB) I undergo testosterone cypionate injections on a weekly basis. As a trans man, I have been receiving testosterone therapy for four years. Recently, I switched to a new hormone specialist and underwent blood testing with him. Historically, my testosterone levels have typically fluctuated between 400 to 600 ng/dL. However, the results from my recent test showed a concerning level of only 67 ng/dL. I have been diligent about my injections, although I did miss one month a few months back due to mental health challenges. Is it possible for testosterone levels to fall so drastically after just a month without a shot? I had the test done six days following my latest injection. I'm left wondering if this level drop is plausible or if it could indicate a mistake in the lab results.
Answers (1)
2/6/2026, 2:00:44 PM
OpenHealth AI
It’s understandable to feel concerned about such a significant drop in your testosterone levels. A result showing 67 ng/dL after typically fluctuating between 400-600 ng/dL can be alarming. While it’s possible for testosterone levels to decrease after missing a dose, this drastic drop warrants further exploration.
Explanation:
- Testosterone Fluctuations: Testosterone levels can fluctuate for various reasons, including hormonal balance, timing of the test relative to your injection schedule, and your body’s absorption of the hormone.
- Impact of Missing a Dose: Missing one month of testosterone injections can definitely impact your hormone levels. However, the extent of the decline and reaching such a low result may suggest either a problem with absorption or the lab measurement rather than solely a consequence of the missed dose.
- Lab Errors: While lab errors can occur, they are less common. Factors such as timing of the blood draw, the specific assay used, or even variations in your body’s hormonal metabolism can impact results.
Next Steps:
- Re-test the Blood Levels: Schedule another blood test to check your testosterone levels again. Ideally, this should be done 24 to 48 hours after your next injection for more accurate results.
- Monitor Symptoms: Keep track of any symptoms you may be experiencing, such as fatigue, mood changes, or any signs of low testosterone, which can help in consultation with your healthcare provider.
- Discuss with Your Specialist: Bring this result to your hormone specialist’s attention. Ask about potential reasons for the discrepancy, and ensure your dosage and treatment plan are reviewed, especially after the missed month.
- Consider Timing: For future tests, consider timing them around when you expect your testosterone levels to be most stable, typically just before your next injection.
You’re not alone in navigating these challenges, and it’s important to work collaboratively with your healthcare team to clarify any concerns and ensure effective management of your hormone therapy. Please keep monitoring how you feel and reach out with any further questions.
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