Understanding Persistent High Levels of CRP
Hello everyone! I'm a 32-year-old woman from the UK and this is my first time sharing on this platform. Recently, I underwent blood tests to look into the cause of microhematuria. While the majority of my test results came back normal, my C-reactive protein (CRP) level was recorded at 7 mg/L, which my general practitioner considered acceptable. However, this raised concerns for me. I am aware that elevated CRP levels can indicate an infection, yet I have had multiple blood tests over the past five years, and the lowest CRP reading during this period was 5 mg/L in 2023, with an average hovering around 8 mg/L. It strikes me as improbable that there could be numerous infections causing this persistent elevation. Therefore, I'm reaching out in hopes that someone might shed light on potential explanations for this ongoing inflammation. A couple of years back, I was referred to a rheumatologist due to experiencing joint pain. They evaluated me and found no signs of rheumatic diseases. I do suffer from some chronic conditions, including Myalgic Encephalomyelitis (ME) and suspected Polycystic Ovary Syndrome (PCOS), and I struggle with being overweight, which complicates efforts to lose weight due to these illnesses. Could my weight be contributing to these inflammatory levels? Currently, I’m only on sertraline for my mental health. I feel hesitant about approaching my GP for further discussion unless I have a clearer idea of what to address, as I worry that my concerns may not be taken seriously. Thank you very much for any insights you can provide! If you require additional information, please feel free to ask.
Answers (1)
2/5/2026, 8:00:52 PM
OpenHealth AI
It's understandable to be concerned about unexplained elevation in your CRP levels, especially with your history of chronic conditions. Managing long-term inflammation can be complex, and your concerns are valid. Here’s a breakdown of what might be happening and actionable steps you can take.
Main Points:
- Elevated CRP Levels: CRP is a marker that indicates inflammation in the body. Your levels being consistently around 7-8 mg/L could point to chronic inflammation rather than acute infection.
- Possible Contributors: Conditions like Myalgic Encephalomyelitis (ME) and Polycystic Ovary Syndrome (PCOS) can influence inflammation. Weight can also contribute, as increased body fat is linked to higher levels of inflammation.
- Next Steps: Focus on lifestyle adaptations and consider discussions with your healthcare provider based on your findings.
Explanation:
- C-reactive protein (CRP): This protein increases in response to inflammation. While a CRP level of 7 mg/L is considered acceptable, for some, it's still worth monitoring, especially if it has been chronically elevated.
- Influencing Factors: Your chronic conditions (ME and suspected PCOS) can lead to persistent inflammation. In conditions like PCOS, hormonal imbalances might affect metabolism and inflammation. Weight can also be a factor since excess weight can lead to chronic low-level inflammation.
Actionable Steps:
- Track Symptoms: Keep a diary of any new or ongoing symptoms related to your conditions. Note any potential triggers (food, activity levels, stress) that coincide with changes in your CRP or overall well-being.
- Lifestyle Adjustments:
- Diet: Consider an anti-inflammatory diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats (like those from fish, nuts, and olive oil). Reducing processed foods and sugars can also help lower inflammation.
- Weight Management: If feasible, aim for a gradual weight loss through balanced nutrition and gentle exercise tailored to your energy levels and fatigue from ME.
- Communicate with Your GP: It’s important to feel heard. Prepare to discuss your CRP levels, your chronic conditions, and any symptoms you experience. Ask if further tests or a referral to a specialist like an endocrinologist could help assess your PCOS or other potential issues related to your inflammation.
- Monitor Stress: Since you are on sertraline for mental health, ensure that you are practicing stress management techniques, such as mindfulness or relaxation exercises, which can also contribute positively to overall inflammation.
Taking these steps may bring clarity and assist in managing your health more effectively. You deserve to have your concerns addressed thoroughly, so don't hesitate to advocate for yourself in discussions with your healthcare provider. If you have any further questions or need more support, feel free to ask!
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