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Considering a Referral Beyond a Nurse Practitioner?

2/5/2026, 9:30:36 AMMale25-34

Age: 35, Height: 5'4", Weight: 125 lbs Presenting Concerns: Prolonged low libido, persistent fatigue. Medical History: - **Fatty Liver Disease**: Diagnosed in February 2025, with subsequent dietary modifications and a weight reduction of 40 pounds over the past year resulting in normalized liver enzymes. - **Endometriosis and Adenomyosis**: Presence of an endometrioma on the left ovary. Underwent a hysterectomy in October 2023, retaining the right ovary; this detail is crucial for understanding my hormonal status without a uterus. Since the birth of my first child around 11 years ago, I have faced challenges with low libido. Despite consulting two different gynecologists, my concerns were dismissed as merely a natural aspect of life. This ongoing issue has caused tension in my marriage, as my husband feels rejected, understandably frustrated by my lack of interest. I sincerely wish to regain my desire. Additionally, I experience a general lack of energy. Working night shifts has complicated my ability to adjust on days off, often leading to insomnia; even when I manage to sleep adequately, fatigue persists. Though I've only been working nights for the last six months, I encountered similar struggles beforehand. Recently, I scheduled an appointment with a new nurse practitioner who claims to have a specialty in hormone therapy. I had an initial evaluation and lab work conducted last week, and I have a follow-up planned for mid-March. The tests included a CBC, CMP, cortisol, hormone levels, vitamin D, vitamin B12, TSH, free T3, free T4, SHBG, and thyroperoxidase. Upon reviewing the lab results, I noted several values that fall outside the normal range, along with many that are borderline abnormal. I will provide a table of the most relevant findings in the comments. The first three in the table are out of range, followed by borderline abnormal results, and then a few mildly abnormal values from the CBC and CMP. The remaining tests listed returned normal results. I was particularly surprised to find my cortisol level to be borderline low, especially as a night worker. This raises questions for me about potential adrenal issues or other underlying conditions. Ultimately, my main inquiry is whether these lab findings necessitate seeking further evaluation beyond the expertise of a nurse practitioner?

AgingWellnessInternal Medicine

Answers (1)

Cony

2/5/2026, 9:30:57 AM

OpenHealth AI

It's understandable to feel frustrated about ongoing health concerns like low libido and persistent fatigue, especially given your history with endometriosis and the challenges posed by night shift work. Your desire for a thorough understanding of your symptoms and lab results is completely valid.

Main Points:

  1. Your lab results indicate abnormalities that could be impacting your energy levels and libido.
  2. Consulting a healthcare provider with further specialization may be necessary, depending on your findings.
  3. Taking proactive steps to address fatigue and libido concerns is essential.

Explanation:

Your unique health history, including a diagnosis of fatty liver disease, the recent hysterectomy, and hormonal imbalances, can influence various aspects of your well-being, including energy levels and sexual desire. Changes in hormone levels post-hysterectomy, dietary modifications, and the effects of working night shifts may also contribute significantly to your symptoms. The borderline low cortisol level particularly stands out and may indeed require further investigation, as it could suggest an adrenal issue or other hormonal imbalances often associated with fatigue and libido changes.

Next Steps:

  1. Review Lab Results with Your Nurse Practitioner: Ensure that you discuss the specific abnormalities noted in your lab tests during your follow-up appointment. Ask about the potential impact of these results on your symptoms. If your nurse practitioner is well-equipped to address these findings, continue working with them.

  2. Consider Specialist Referral if Needed: If your nurse practitioner cannot provide clear answers or an effective treatment plan, it may be worthwhile to seek further evaluation from an endocrinologist or a reproductive endocrinologist. These specialists focus on hormonal issues, which are crucial given your concerns.

  3. Lifestyle Modifications for Fatigue: Focus on improving your sleep quality and overall energy:

    • Create a consistent sleep routine, even on your days off, to help regulate your body clock.
    • Use relaxation techniques before sleep, such as deep breathing or gentle stretching.
    • Maintain a balanced diet rich in whole foods, with ample proteins, healthy fats, and complex carbohydrates to steady your energy levels.
  4. Support and Communication: Be open with your husband about your journey and frustrations. Counseling or support groups can also be beneficial for both of you in navigating these changes together.

  5. Keep a Symptom Diary: Documenting your energy levels, mood, and libido alongside any changes related to your work schedule and lifestyle can help identify patterns and triggers, which will be useful during your consultations.

You're taking an important step by addressing these health concerns, and with the right support, there is potential for improvement. Let me know if you have further inquiries or need additional suggestions!

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