Understanding Abnormal NRBCs and MCHC Levels
To provide some background, I am a 26-year-old female, standing at 5 feet 7.5 inches and weighing 135 pounds. I don't smoke and only drink socially. Last year, I faced a significant health issue when my lung collapsed, requiring me to undergo surgery in late October—specifically a VATS talc pleurodesis and wedge resection. My recovery from the surgery has been generally smooth, and I've been feeling progressively better. However, in early January, I began experiencing shortness of breath along with intermittent body aches and occasional chest pain. To rule out the possibility of a returning pneumothorax, I sought medical attention and had a chest X-ray, which fortunately came back clear. Nevertheless, I received some concerning lab results showing anomalies in my MCHC and NRBC levels. The MCHC reading was 31.4 g/dL; while it was slightly low for me on occasion, it didn’t raise major concerns. Conversely, my NRBC count registered at 0.4 /mL, which is abnormal since it should typically be zero and has never exceeded that threshold in previous tests. Although this figure seems low, a nurse friend of mine mentioned that NRBC counts tend to rise only in severe medical conditions, like leukemia or significant bone marrow issues. I have no notable medical history aside from being diagnosed with PCOS, and I presently take only multivitamins each day. Unfortunately, my primary care physician is unavailable due to a family tragedy, so I’m left wondering whether I should be concerned about these lab results.
Answers (1)
2/5/2026, 12:01:20 AM
OpenHealth AI
It sounds like you’re understandably worried about your recent lab results, especially with your health history. The presence of nucleated red blood cells (NRBCs) and your MCHC levels can be concerning, but there are several things to consider.
Main Points:
- NRBCs in the blood are typically a sign that the bone marrow is responding to stress, but they can occasionally appear in less severe conditions.
- Your MCHC level was slightly low, which may be unrelated to the NRBC findings.
- Given your recent lung surgery and current symptoms, it's essential to monitor your health closely.
Explanation
NRBCs (nucleated red blood cells) are immature red blood cells that usually shouldn’t be found in the bloodstream in adults except in cases of significant stress or bone marrow response. Seeing them at lower levels, as in your case (0.4 /mL), can arise from various situations, including recovery from an acute condition or inflammation.
Your MCHC (Mean Corpuscular Hemoglobin Concentration) value being low may reflect mild anemia or hydration status, but since it has been fluctuating, it isn’t a major red flag on its own.
Next Steps
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Monitor Symptoms: Keep track of your shortness of breath, body aches, and chest pain. Note if there are any changes in their frequency or severity.
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Stay Hydrated and Nourished: Ensure you're drinking plenty of fluids and eating a balanced diet rich in iron and vitamins; this can help if you're experiencing mild anemia.
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Follow Up with Your Doctor: Since your primary care physician is currently unavailable, consider contacting another physician or a local clinic to discuss your lab results. Ask them if further tests or monitoring are needed.
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Emergency Signs: If you experience worsening chest pain, severe shortness of breath, or any new concerning symptoms like dizziness or fainting, seek medical attention immediately.
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Lifestyle Considerations: Manage your stress levels and incorporate gentle physical activity, as tolerated, to help with your overall recovery and lung function.
While it’s normal to have concerns about lab results, many factors can influence these numbers, especially following a recent surgical recovery. Keep track of your health and reach out for professional guidance when available. Take care!
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