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Seeking Help: Week-long Battle with Oral White Coating

2/4/2026, 10:30:24 AMMale25-34

Greetings everyone, I am a 25-year-old male and I want to share my current health struggle. To clarify, I am HIV negative, do not have AIDS, diabetes, or any identified immune system issues. Recently, I observed an alarming change in my oral health — my entire mouth appeared to have a white hue. This included my tongue (both top and sides, and later the underside), the insides of my cheeks, the roof of my mouth, the uvula, and even my lips. The white film was thick, with some areas being quite painful. During a gentle attempt to scrape my gums, a large white patch came off excruciatingly. Additionally, I noticed whitish spots appearing on my lips. While I haven’t experienced any fever or severe dental pain, I have been dealing with general soreness, a burning sensation, and these white patches, some of which seem to peel. My tongue has been a significant source of discomfort. I’ve been to two different hospitals, and each provided me with different opinions, adding to my confusion. At the first facility, the physician suggested I might have oral thrush and recommended fluconazole 200 mg twice daily for a week, along with an antifungal gel (miconazole). The second hospital conducted blood tests, all of which returned normal results. The doctor there advised me to cease taking fluconazole and instead prescribed co-amoxiclav 625 mg. This inconsistency has left me in a state of uncertainty, especially since my symptoms strongly resemble those of oral thrush. From what I know, antibiotics typically do not address fungal infections and could potentially exacerbate the issue. As a result, I’ve opted to continue with fluconazole and use the miconazole gel, while forgoing the antibiotic altogether. Complicating matters further, my symptoms fluctuate drastically from day to day—some days I see improvement, while other days my tongue appears worse, heightening my anxiety. I’ve been dealing with this condition for only a week, and I’ve never experienced anything like it before. I would appreciate it if anyone could share insights or experiences related to symptoms like mine. Here are my concerns: 1. Is it normal for oral thrush to cause a significant white coating throughout the mouth, including the lips and uvula? 2. Are there other potential causes for these symptoms aside from thrush? I’ve been grappling with this issue for a week and it’s taken a toll on my mental well-being. Thank you for taking the time to read my post.

VomitingGastroenterologyInternal Medicine

Answers (1)

Cony

2/4/2026, 10:30:45 AM

OpenHealth AI

Thank you for sharing your experience; I understand how distressing this situation can be. The symptoms you describe — a thick white coating in your mouth, including painful areas and whitish spots on your lips — can indeed relate to oral thrush, but other possibilities also exist.

Main Points

  1. Oral thrush can cause a persistent white coating throughout the mouth, including the tongue, cheeks, and sometimes the lips and uvula.
  2. Other potential causes for your symptoms might include leukoplakia, lichen planus, or even reactions to medications or irritants.
  3. The fluctuation in symptoms may indicate an underlying irritation or an ineffective treatment approach.

Explanation

Oral Thrush: This is a fungal infection caused by an overgrowth of Candida yeast. It typically presents as a white coating in the mouth, which can often be scraped off, sometimes leaving painful redness behind. The discomfort you're experiencing aligns with this diagnosis.

Other Causes:

  • Leukoplakia: Thick, white patches in the mouth can be related to irritation, often due to tobacco use or friction.
  • Lichen Planus: This inflammatory condition can also cause white patches and soreness, sometimes resolving with time or treatment.
  • Irritants: Certain medications, including antibiotics like co-amoxiclav, can disrupt the oral flora and lead to irritations or infections.

Next Steps

  1. Continue with Fluconazole and Miconazole: Since you're experiencing discomfort indicative of oral thrush, sticking with the antifungal treatment appears to be the most logical approach. Monitor how your symptoms respond over the next few days.

  2. Maintain Oral Hygiene: Rinse your mouth with warm salt water several times a day to help soothe irritation. It's gentle and can assist in maintaining cleanliness without adding to discomfort.

  3. Identify Irritants: Avoid spicy, acidic, or crunchy foods which could exacerbate your symptoms. If applicable, try to eliminate any recent oral hygiene products or medications that could contribute to irritation.

  4. Symptom Diary: Keep a record of your symptoms, any new changes, and potential triggers (foods, medications, etc.) to help you identify patterns over time, which can be discussed with your healthcare provider.

  5. Monitor for Changes: If symptoms worsen, persist beyond a week of treatment, or new symptoms arise (e.g., fever, severe pain, difficulty swallowing), it's essential to reassess your treatment plan; consider seeking another medical opinion if necessary.

It’s understandable that this situation is causing you anxiety, especially given the fluctuating nature of your symptoms. Prioritize self-care and be gentle with yourself during this time, keeping an open line of communication with your healthcare team about your treatment and progress. Please feel free to share updates or ask further questions.

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