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Experiencing an Allergic Reaction to Medication: Should I Seek Emergency Help?

2/4/2026, 2:50:20 AMMale25-34

I’m a 26-year-old female. After taking my first dose of Nitrofurantoin mono/mac 100mg capsules, I started to feel a burning sensation in my neck within just a couple of hours, accompanied by noticeable redness. This discomfort soon extended to my face and upper chest, and the burning has become quite intense. I decided to reach out to the pharmacy, where the pharmacist recommended that I take Benadryl. He advised that if I experienced any itchiness in my throat or if it felt like it was closing up, I should urgently visit the emergency room. I’ve just taken the Benadryl, but I can’t shake off my concerns. How long should I remain awake to ensure I’m alright?

Drug AllergiesAnaphylaxisAllergy & Immunology

Answers (1)

Cony

2/4/2026, 2:50:39 AM

OpenHealth AI

It's understandable to feel concerned after experiencing troubling symptoms following a new medication. Based on your description, it seems you may be having an allergic reaction to Nitrofurantoin, which can include symptoms like burning sensations, redness, and discomfort.

Key Points:

  • Your Symptoms: Burning sensation and redness after taking Nitrofurantoin may indicate a possible allergic reaction.
  • Emergency Signs: It's crucial to be aware of any worsening symptoms, especially throat itchiness or swelling, which could signal a more serious reaction needing immediate medical attention.

Explanation:

Allergic reactions can vary in severity. The mild symptoms you're experiencing (burning and redness) can sometimes progress. The pharmacist’s advice is prudent; quick action is vital if threatening symptoms develop. Since you’ve taken Benadryl, it should help reduce mild allergic symptoms by blocking histamines.

Next Steps:

  1. Monitor Symptoms Closely: Keep an eye on how you feel over the next few hours. If you notice any hitting thresholds like itchiness in your throat, difficulty breathing, or significant swelling anywhere on your body, seek emergency medical help immediately.

  2. Stay Awake for a While: It's generally advised to stay awake for 2-4 hours after taking Benadryl, as you want to ensure you’re stable and alert while the medication is taking effect. Setting a timer for symptoms may help.

  3. Hydration and Comfort: Drink plenty of water to stay hydrated, and consider cool compresses on any areas of discomfort to alleviate burning sensations.

  4. Avoid Allergenic Triggers: If you suspect the medication caused your reaction, avoid taking any more of it until you discuss it with a healthcare professional.

  5. Follow-Up: After the immediate situation stabilizes, consider discussing your symptoms with your healthcare provider for future management and potential alternatives to Nitrofurantoin.

Reminder:

If at any point your symptoms change or escalate, do not hesitate to go to the emergency room or call emergency services. Your health and safety are the most important factors.

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