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Chronic Nausea for Seven Years

2/3/2026, 6:30:22 PMMale25-34

My daughter, who is now 23, has been struggling with persistent nausea since the age of 16. Initially, she experienced considerable weight loss, prompting us to seek medical advice. After visiting her primary care physician, she was referred to a specialist in gastrointestinal issues. They performed an endoscopy, but the results showed no abnormalities. Consequently, she had to manage her condition on her own. Over time, she adapted to the persistent nausea and began using Zofran nearly every day. We later discovered that her symptoms seemed to coincide with the initiation of the depo shot for contraception. After switching to birth control pills, she noticed slight improvements, but her symptoms have worsened again as time has progressed. A few months ago, she underwent blood tests, including evaluations for food allergies, but everything came back normal yet again. At this stage, I am at a loss regarding the next steps or which specialist to consult. She experiences bouts of nausea primarily after meals, impacting her comfort. Despite this, she has adapted enough to remain functional, especially since she regained the weight she lost within a year. I am feeling quite helpless in this situation. Any suggestions or advice would be greatly appreciated.

Crohn's DiseaseThyroid DisordersInternal Medicine

Answers (1)

Cony

2/3/2026, 6:30:44 PM

OpenHealth AI

I'm sorry to hear that your daughter has been dealing with chronic nausea for such a long time. This can be incredibly challenging for both of you, and it’s understandable to feel lost when navigating her health journey. It sounds like you've made significant efforts to investigate the issue, and it's commendable that she has managed to regain weight.

Key Points:

  1. Persistent Nausea Causes: Several factors can contribute to chronic nausea, including gastrointestinal issues, hormonal influences, and more.
  2. Medication Side Effects: The nausea worsened after the depo shot, suggesting a possible link that might require reevaluation.
  3. Next Steps: Exploring comprehensive dietary changes, potential medication alternatives, and possibly seeking specialists with specific expertise may help.

Explanation:

Chronic nausea can stem from various causes such as gastrointestinal disorders (like gastroparesis), hormonal imbalances, stress, or even reactions to medications like hormonal contraceptives. Since she had slight improvements after switching from the depo shot to birth control pills, it’s worthwhile to investigate hormonal influences more deeply.

The endoscopy and allergy tests being normal are positive, but it indicates that the issue might not be easily visible or purely physical. Environmental, emotional, or dietary factors could also be influencing her symptoms.

Actionable Next Steps:

  1. Track Symptoms and Diet: Encourage her to keep a food and symptom diary. Documenting what she eats and when nausea occurs can help identify potential triggers, including food sensitivities not covered in allergy tests.

  2. Reassess Contraceptive Options: Discuss the potential relationship between her nausea and her birth control. It might be worth trying a different form or method of contraception that doesn’t involve hormones, if agreed upon with a healthcare provider.

  3. Speak to a Gastroenterology Specialist: Seek a second opinion or a gastroenterologist specializing in functional gastrointestinal disorders or motility issues. They can offer fresh insights or further investigations, such as gastric emptying studies.

  4. Consider Psychological Support: Chronic nausea can sometimes have a psychological component. Consulting with a mental health professional who specializes in chronic illness could provide supportive strategies and coping mechanisms.

  5. Medication Review: Since she’s using Zofran regularly, it’s vital to reassess her treatment plan. Discuss with a healthcare provider the frequency of use and explore whether alternating medications or adding anti-nausea alternatives could be beneficial.

Encourage her through this journey, ensuring she knows she’s not alone in this complex situation. Small, thoughtful adjustments can make a significant difference over time. Please feel free to reach out for more specific information on any of these areas!

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