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Seeking Assistance from a Dermatologist

2/3/2026, 5:40:16 PMMale25-34

At 25 years old, I’m facing a troubling issue on my upper lip resembling a canker sore. This all began about two weeks ago when I first noticed a pus-filled blister, and it has since evolved into a painful, white ulceration. The discomfort is quite severe, causing significant stinging. I've been using tacrolimus 0.03% ointment for my upper lip eczema for an extended period, alongside ucera cream that was prescribed to me. While my eczema symptoms have improved somewhat, this painful irritation has yet to resolve.

ArthritisEndocrinologyRheumatology

Answers (1)

Cony

2/3/2026, 5:40:37 PM

OpenHealth AI

It sounds like you're experiencing a painful sore on your upper lip that has developed recently and is causing significant discomfort. This may be a separate issue from your eczema and could potentially be an infection or a reaction to a treatment. Addressing your symptoms and finding relief is essential.

Explanation:

The description of a pus-filled blister that has progressed to a painful, white ulceration could indicate several possibilities, such as a herpes simplex infection (cold sore), a canker sore, or an infection related to the use of tacrolimus. Each of these has differing treatment approaches, so understanding the exact cause is crucial.

Next Steps:

  1. Avoid Irritants: Refrain from using lip products or other topical treatments on the affected area that might further irritate your skin.

  2. Do Not Pick or Squeeze: Resist the urge to touch or pick at the ulcer, as this can worsen irritation and risk infection.

  3. Symptom Relief: You may consider using over-the-counter pain relief methods such as:

    • Topical analgesics (e.g., benzocaine) to reduce pain.
    • Cold compress: Applying a clean, cold cloth to the affected area can help soothe pain and reduce inflammation.
  4. Keep the Area Clean: Gently cleanse the affected area with mild soap and water to minimize the risk of infection.

  5. Monitor Changes: Keep an eye on the sore. If it does not improve within a few days, or if you notice fever, increased pain, or if the sore spreads, it might be necessary to consider stronger intervention.

  6. Considerating Review of Medications: Although tacrolimus is beneficial for eczema, if you're noticing worsening symptoms in different areas, this should be addressed.

If these symptoms persist or worsen, it may ultimately be necessary to consult with a dermatologist to determine the exact cause and get tailored treatment options. Let me know if you have further questions or need more information!

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