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Understanding the Causes of Diffuse Burning Sensation: Neuropathic, Autoimmune or Stress-Related?

2/3/2026, 1:30:22 AMMale25-34

**Age:** 35 **Gender:** Female **Duration:** Experiencing symptoms for approximately three months; had similar issues last year which eventually subsided. **Medications:** Occasionally take Vitamin D. **Lifestyle Factors:** No smoking or drug use. **Medical History:** Struggles with significant anxiety and depression. Hello, I'm seeking advice as I await the results of my ongoing tests. I’ve been dealing with a **burning sensation** akin to the feeling of being too close to a flame. This discomfort predominantly affects my **thighs and abdomen**, but I have also felt it in my **lower back, arms, and calves**. - The level of pain varies, ranging from **mild discomfort to severe agony**. - The sensation is not localized and tends to shift locations. - Sometimes, standing up or stretching provides relief. - There is no identifiable trigger for these symptoms. **Additional Information:** - I experience **high levels of anxiety**, and my neurologist has noted similar sensations linked to anxiety-based conditions. - However, I’ve never encountered burning sensations related to my anxiety previously, which makes me question how valid this explanation is. **Diagnostic Journey Thus Far:** - Consulted with a **neurologist**; symptoms do not align with MS. - Recent blood tests indicated slightly elevated cholesterol and a **high ANA level**, though I’ve been informed this could be nonspecific. - **MRI** is currently pending. - I have an upcoming appointment with **rheumatology**. **Inquiries:** 1. Is it possible for anxiety to induce **widespread burning sensations** like this, despite having no prior similar experiences? 2. Does the **intermittent nature** of these sensations point more towards neuropathic or autoimmune origins? 3. If the investigations yield no answers, which medical specialty should I consider consulting next? Thank you for taking the time to assist me.

AnxietyDepressionStress

Answers (1)

Cony

2/3/2026, 1:30:39 AM

OpenHealth AI

Thank you for sharing your concerns about the burning sensations you've been experiencing. Here’s a concise overview and guidance tailored to your situation.

Main Points:

  1. Anxiety can indeed lead to physical sensations like burning, even if this is a new experience for you.
  2. The shifting and intermittent nature of your symptoms can be linked to different underlying causes, and further investigation is warranted.
  3. If no answers arise from your current evaluations, a consultation with a pain specialist or a psychiatrist experienced in somatic disorders may be beneficial.

Explanation:

The burning sensation you describe could arise from several factors, including anxiety, neuropathic issues, or autoimmune conditions. Anxiety can manifest physically in different ways, even if certain experiences are new. The body's response to stress may cause sensations like burning or tingling, which can fluctuate in intensity and location.

Given your medical history and recent findings (like elevated ANA levels), you're right to explore potential autoimmune components. However, the somewhat elusive nature of your discomfort can sometimes also indicate a neuropathic component or be stress-induced.

Next Steps:

  1. Monitor Symptoms: Keep a daily journal of your symptoms. Note when they occur, their intensity, and any activities that seem to alleviate or worsen the sensations. This information can be valuable to your healthcare providers.

  2. Daily Self-Care: Incorporate relaxation techniques such as deep breathing, mindfulness, or meditation to help manage your anxiety. This might also assist in alleviating your physical symptoms.

  3. Stay Engaged with Specialists: Continue your journey with the neurologist and rheumatologist. Discuss your findings with them, especially the shifting nature of your sensations.

  4. Consider Next Steps if Necessary: If your symptoms persist without a clear diagnosis after your upcoming appointments, consider speaking with a pain management specialist or a mental health professional who can help address somatic symptoms linked to anxiety.

Take care to stay connected with supportive friends or family and don’t hesitate to reach out if you need additional assistance or clarity. You deserve attention and support as you navigate this challenging experience.

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