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Ongoing Dilated Pupil Concerns

12/16/2025, 9:00:37 PMMale25-34

As a 27-year-old female diagnosed with asthma, I currently rely on Spiolto Respimat, Qvar 100, and Ventolin to manage my condition. Yesterday morning, I observed a concerning difference in my pupils – my left pupil was significantly larger than the right. This isn’t the first instance of this happening; I experienced a similar situation a few weeks prior, which self-resolved after a day. Given that this was the second occurrence, I felt compelled to seek professional advice, fearing that a more severe issue might be present. I reached out to my general practitioner, who subsequently referred me to an ophthalmologist. The eye specialist conducted various tests and used pilocarpine drops, yet the size of my pupils did not change. Eventually, he inferred that the dilation of my pupil was likely a side effect of tiotropium and reassured me that it should normalize over time. He also mentioned that if the condition persisted, it would be prudent to consult my pulmonologist regarding a potential connection to my asthma medication. Today, I had a phone consultation with my pulmonologist to address my concerns. He deemed it improbable that the medication was the cause because the symptoms are unevenly presented, and such timing after prolonged use seems unlikely. While I haven’t yet brought this up with my ophthalmologist, I intend to discuss it during my online appointment this Thursday. I felt fine yesterday despite a slight nausea and an odd sensation in my left eye. However, today, the nausea has increased, particularly in the mornings and following meals, and my left pupil remains dilated. This has sparked worries that the cause may not be tiotropium as previously thought, and there could be another underlying issue. I am seeking guidance on potential explanations for my symptoms, their possible correlation with my medication, and recommendations for next steps should this condition continue.

AsthmaInternal MedicineEndocrinology

Answers (1)

Cony

12/16/2025, 9:00:56 PM

OpenHealth AI

It sounds like you're experiencing a concerning and persistent issue with your dilated pupil, along with some new nausea. While your ophthalmologist has suggested that the dilated pupil could be a side effect of your asthma medication (tiotropium), it’s understandable that you want to explore other possible explanations due to the recurring nature of your symptoms and their connection to your overall well-being.

Key Points:

  • Recurrent pupil dilation, particularly if it is accompanied by nausea and odd sensations in the eye, should be taken seriously.
  • Possible causes for your symptoms can include medication side effects, neurological conditions, or other eye-related issues.

Explanation:

  1. Medication Effects: Some medications can cause pupil dilation as a side effect. While your pulmonologist believes it’s unlikely related to tiotropium due to the timing and presentation, it’s still a possibility that warrants discussion.

  2. Neurological Causes: The combination of a dilated pupil and nausea could point to a neurological issue, such as increased intracranial pressure or other central nervous system disorders, which can result in autonomic dysfunction affecting pupil size.

  3. Eye Health: An abnormal pupil size can also indicate certain eye conditions, such as Horner's syndrome (often due to nerve damage) or iris abnormalities. It’s good that you’re keeping your follow-up appointment with the ophthalmologist, as they can provide more targeted insights.

Actionable Next Steps:

  1. Follow Up with Your Ophthalmologist: Bring up the new symptoms (increased nausea and sensations in your left eye) during your upcoming appointment. Do not hesitate to express your concerns about a potential neurological cause if the dilation persists.

  2. Monitor Symptoms: Keep a detailed record of your symptoms, including when the pupil dilation occurs, any associated symptoms like nausea, and their severity. This documentation can help your healthcare team identify patterns.

  3. Consider Medication Review: Mention your concerns to both your pulmonologist and ophthalmologist about the possibility of medication side effects. If appropriate, a medication adjustment might be explored.

  4. Maintain Open Communication: If your symptoms worsen, such as experiencing severe headaches, vision changes, or if new symptoms arise, it's essential to seek immediate medical help.

Remember, your health concerns are valid, and it's important to continue advocating for yourself with your healthcare providers. You're taking the right steps by seeking professional evaluations and clarifications. Please keep communication lines open with your doctors about all your symptoms and concerns moving forward.

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