Unexpected Weight Loss of Over 30 Pounds in Three Months – Seeking Guidance
Greetings, I’m a 30-year-old female. At the start of September, I weighed in at 210 pounds, but I've dropped to 175 pounds since then. I'm at a loss to explain this sudden change in my weight and health. I've consulted several doctors and undergone both a colonoscopy and an endoscopy. Here’s what I’ve been experiencing: an inability to eat normally; even when I try, I can only manage a few bites before feeling incredibly full. I’m suffering from severe abdominal pain and cramps, particularly sharp discomfort in the upper part of my abdomen. An ultrasound and various blood tests yielded normal results, which leaves me perplexed. For over three months, my intake has not exceeded 10 bites of food in one sitting. Although I’m not tracking my calories, I estimate that my daily consumption might be around 500 calories. To ensure I receive some nutrition and protein, I've started drinking nutritional shakes. I’ve researched my symptoms online and found an extensive list of possible conditions. While I'm aware a definitive answer may not be possible, I am looking for advice on pertinent questions to discuss with my doctors during my next appointment in a couple of weeks. The pain in my stomach is overwhelming, and I just want to be able to eat normally again. In terms of diagnosis, the results indicated the following: - **Small Bowel, Duodenum Biopsy:** Mild intraepithelial lymphocytosis detected in the duodenal mucosa. - **Stomach Biopsy:** Found body/fundic-type mucosa with minimal chronic inflammation. No Helicobacter organisms were identified. - **GE Junction Biopsy:** Revealed small cardiac mucosa with chronic inflammation, and negative results for intestinal metaplasia or dysplasia. Mild reflux-type changes were noted in the squamous mucosa. Additionally, there is a suspicion that I might be showing early signs of celiac disease. Thank you for taking the time to read my post; I’d greatly appreciate any advice you might have!
Answers (1)
12/16/2025, 8:50:39 PM
OpenHealth AI
Main Points: Sudden and significant weight loss, inability to eat, abdominal pain, and potential celiac disease require careful monitoring and specific discussions with your healthcare team. Addressing your concerns with focused questions can lead to clearer insights into your condition and treatment options.
Explanation: It's understandable to feel anxious regarding dramatic weight loss and ongoing abdominal pain. These symptoms can arise from various causes, including digestive disorders, dietary intolerances, or other underlying conditions. Your prior tests have ruled out some serious issues, but your symptoms still need a thorough examination, particularly regarding the potential early signs of celiac disease. If undiagnosed or untreated, celiac disease may cause ongoing digestive issues and malnutrition.
Your significant weight loss and reduced food intake are concerning and may lead to long-term health issues if not addressed. Drinking nutritional shakes is a positive step towards meeting your caloric and nutritional needs, but it’s crucial to identify the root cause of your symptoms to manage them effectively.
Next Steps:
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Prepare Questions for Your Doctor:
- Can we further investigate the potential diagnosis of celiac disease with specific blood tests (like tTG-IgA) or an oral food challenge?
- Should we consider additional imaging or tests, like a repeat endoscopy or specific gastrointestinal studies?
- What dietary changes should I explore while awaiting a diagnosis, especially if celiac disease is suspected? Should I try a gluten-free diet?
- Are there medications or treatments that could alleviate my abdominal pain?
- Could there be other conditions causing similar symptoms that we haven't explored yet (e.g., gastroparesis, thyroid issues)?
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Monitor Symptoms:
- Keep a daily symptom diary, noting food intake, pain levels, and how you feel after eating. This can provide valuable insights for your doctor.
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Dietary Adjustments:
- Consider consulting a nutritionist to ensure your dietary choices are supporting your health and easing your symptoms.
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Prioritize Self-Care:
- Focus on hydration and gentle meals that are easy to digest (like broths, smoothies, and easily digestible grains) to ensure you’re getting enough nutrients.
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Plan for Follow-Up:
- Stay in close contact with your healthcare providers, especially if your symptoms worsen or new symptoms arise.
Feeling overwhelmed is normal, but remember, you are advocating for your health by reaching out for guidance. Best of luck at your upcoming appointment; having these discussions can lead toward better answers and relief.
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