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Seeking Answers for My Brother's Ongoing Health Struggles: Age 31

9/15/2025, 2:40:26 AMMale25-34

My brother has been experiencing persistent inflammation, particularly affecting his ankles and knees. For more than a year and a half, he has faced significant mobility challenges, making it impossible for him to walk without assistance. Despite numerous consultations with various doctors who have conducted extensive testing, we have yet to uncover any definitive explanation or solution for his condition. Instead, he has been shuffled from laboratory to laboratory for over a year, leaving us in the dark about his health issues. In my quest to help him, I recently obtained his medical test results, and I'm eager to decipher them, especially given my concerns that his condition may deteriorate further. Here are the highlighted abnormal findings from his tests: - WBC: 14.6 (Elevated) - Hemoglobin: 12.8 (Decreased) - Platelets: 501 (Elevated) - Neutrophils (Absolute): 11.5 (Elevated) - Creatinine: 1.29 (Elevated) - BUN/Creatinine Ratio: 5 (Decreased) - Albumin: 3.8 (Decreased) - A/G Ratio: 1.1 (Decreased) - HDL Cholesterol: 36 (Decreased) - LDL Cholesterol: 125 (Elevated) - Hemoglobin A1c: 6.1 (Elevated) - TSH: 0.27 (Decreased) - Urinalysis: Appearance Cloudy (Abnormal) - Urinalysis: Protein 1+ (Abnormal) - Urinalysis: RBC 11–30 /hpf (Abnormal) I hope to find some clarity regarding these results and seek a pathway to improve his situation.

AgingInternal MedicinePreventive Medicine

Answers (1)

Cony

9/15/2025, 2:40:45 AM

OpenHealth AI

It sounds like your brother is facing significant health challenges with persistent inflammation and mobility issues, and it's understandable that you're seeking clarity regarding his test results. Let's break down the abnormal findings and provide some guidance on next steps.

Summary of Key Concerns:

  1. Elevated White Blood Cells (WBC) and Neutrophils: Suggests an inflammatory or potential infectious process.
  2. Decreased Hemoglobin: Indicates possible anemia, which can affect energy levels and overall health.
  3. Elevated Creatinine and BUN/Creatinine Ratio: May indicate kidney involvement.
  4. Albumin and A/G Ratio: Decreased levels may suggest issues with protein production or kidney function.
  5. Metabolic Indicators: Elevated LDL cholesterol and Hemoglobin A1c signal cardiovascular risk and potential prediabetes.
  6. Urinalysis Findings: Protein and red blood cells in urine signal potential kidney issues or inflammation.

Explanation:

These results suggest several possible issues, including inflammatory conditions (like arthritis or autoimmune disease), kidney involvement, and metabolic concerns that could collectively contribute to his inflammation and mobility problems.

Prioritized Next Steps:

  1. Consult a Specialist: Given the complexity of your brother's situation, a rheumatologist (for inflammation and potential autoimmune issues) or a nephrologist (for kidney health) may provide the most targeted insights and targeted diagnostic tests.
  2. Focus on Dietary and Lifestyle Changes: Encourage a balanced diet rich in anti-inflammatory foods (like fruits, vegetables, whole grains, and healthy fats) while limiting processed foods and sugars. This can support overall health and reduce inflammation.
  3. Monitor Symptoms Closely: Keep a journal of his symptoms, noting any changes in inflammation, mobility, or fatigue. This information can help healthcare providers better understand his condition over time.
  4. Engage in Gentle Physical Activity: If manageable, activities like stretching or gentle exercises can improve joint mobility and range of motion. Consult a physical therapist for tailored exercises that suit his condition.
  5. Maintain Regular Follow-ups: Regular evaluations with healthcare providers to monitor changes in blood work, symptoms, and kidney function are essential to adapt the management plan as necessary.

Closing Thoughts:

It's understandable to feel overwhelmed when dealing with complex health issues, especially when numerous tests have been performed without clear answers. Encourage your brother to stay engaged with his healthcare, and your support can make a meaningful difference in navigating this journey together. If any new symptoms arise or there are significant changes in his condition, it’s important to address those promptly.

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