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Understanding Sheehan's Syndrome

9/15/2025, 1:50:21 AMMale25-34

Being eight weeks postpartum, I recently visited my endocrinologist to go over the results of my blood tests related to my hypothyroidism. During our discussion, he probed into topics like my breastfeeding experience (noticing a drop in supply and low prolactin levels) and my recent weight fluctuations. He suggested that I undergo another blood evaluation to check for the possibility of Sheehan’s Syndrome. Here are some of the notable hormone levels: - ACTH Plasma: 107 pg/mL - Prolactin: 35.9 ng/mL - DHEAS: 49 mcg/dL I am currently awaiting results from an AM cortisol test. Although my results show some levels outside the normal range, I am uncertain about their implications. Is it possible for Sheehan’s Syndrome to present alongside elevated ACTH? I'm curious if anyone has dealt with similar test results and what diagnosis they received. My labor, delivery, and recovery journey have been fraught with challenges, leaving me feeling exhausted. My hope is to gain clarity on my situation.

Thyroid DisordersEndocrinologyRheumatology

Answers (1)

Cony

9/15/2025, 1:50:38 AM

OpenHealth AI

It's understandable to feel overwhelmed after a challenging postpartum experience, especially when dealing with hormonal issues. Sheehan's Syndrome is a condition that can arise due to severe blood loss during or after childbirth, leading to damage in the pituitary gland. The concerns you have regarding your hormone levels and their implications are valid, and I’ll help clarify a few points.

Key Points:

  1. Sheehan's Syndrome Symptoms: This condition can present with a range of hormonal imbalances, including low levels of key hormones, fatigue, and difficulties in breastfeeding due to insufficient prolactin.
  2. ACTH Levels: Elevated ACTH may suggest that your body is trying to stimulate the adrenal glands, but it doesn’t definitively indicate Sheehan’s Syndrome, as this condition typically involves low cortisol levels rather than elevated ACTH alone.

Explanation:

  • Prolactin Levels: Your prolactin level of 35.9 ng/mL might indicate a mild hyperprolactinemia, which can sometimes stem from stress, certain medications, or pituitary issues.
  • Cortisol and ACTH: The AM cortisol test you are awaiting will be crucial. If cortisol is low and ACTH is high, this could indicate an adrenal gland issue or potentially Sheehan's Syndrome. Conversely, normal cortisol levels with high ACTH might suggest other conditions such as pituitary dysfunction.

Next Steps:

  1. Await AM Cortisol Results: This will provide more clarity regarding your adrenal function.
  2. Monitor Symptoms: Keep track of any other symptoms like fatigue, weight changes, or mood fluctuations. This information can help tailor your care.
  3. Discuss Further Testing: Depending on the results of your AM cortisol test, additional hormone evaluations (like thyroid hormones, other pituitary hormones) might be recommended by your endocrinologist.
  4. Support and Self-Care:
    • Focus on self-care through adequate hydration, nutrition, and rest.
    • Join support groups or communities for new parents to share experiences and coping strategies, which can provide emotional relief.

Your situation can be complex, and it’s important to keep the lines of communication open with your healthcare team. If you have any further concerns or experience worsening symptoms, consider reaching out promptly for assistance. You're taking important steps toward understanding your health, and clarity will come with patience and informed follow-up.

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