Painless Hard Nodule Under Chin Following Thyroid Medication Adjustment
Age: 21 Height: 5’ 1” Never smoked, and I don’t consume alcohol. Medications: Levothyroxine 100 mcg (dose raised from 88 mcg in early August 2025) Medical Background: Hypothyroidism with no recent infections and no family history of cancer Duration of the Issue: Noticed the lump on September 12, 2025 (just two days ago) Details: - I have been taking levothyroxine to manage my hypothyroidism, and my medication dose was recently increased due to elevated TSH levels. - Approximately four to five weeks post-dose adjustment, I started experiencing noticeable hair thinning. - Just two days ago, I discovered a small, firm, non-movable lump beneath my chin in the upper neck area, positioned slightly to one side. - I have not experienced any symptoms such as sore throat, fever, or indications of infection. - During the same week that I found the lump, I also observed a new mole on my skin and noticed an increased craving for coffee. Inquiry: Is it possible that this lump is associated with my thyroid condition or the medication adjustment, or could it signify something more concerning, like cancer? I’m eager to understand how urgent this situation might be and whether I should seek an ultrasound promptly. Feeling a bit anxious about this! 😭
Answers (1)

9/14/2025, 5:01:17 AM
OpenHealth AI
It's understandable to feel anxious about a new lump, especially after a recent change in your medication. Let’s break this down and provide clarity on your situation.
Main Points:
- A hard nodule under your chin after an increase in levothyroxine dosage could possibly be related to benign causes, such as a swollen lymph node or a thyroid-related issue.
- The absence of infection symptoms is reassuring, but the lump's persistence should be monitored.
- It's important to consider other changes, like new moles and increased cravings for coffee, that might suggest a need for follow-up.
Explanation:
The lump you're feeling beneath your chin is likely a lymph node, which can become enlarged due to various non-serious causes, such as a reaction to changes in hormones from your medication or even minor irritations. It’s less common for lumps caused by thyroid issues or medication adjustments to present suddenly and become noticeable so quickly.
- Thyroid connection: While levothyroxine is used to correct hormone levels in hypothyroidism, significant dose changes can cause various side effects, including changes in hair density and possibly other systemic effects.
- New mole observation: Noticing a new mole, especially combined with other changes, is worth noting but not panicking over.
Next Steps:
-
Monitor the Lump:
- Observe any changes in size, firmness, or if new symptoms develop (like pain or redness). Take notes on any significant changes.
-
Self-Care:
- Maintain a routine of consistent medication adherence. Ensure your dosage and timing are followed as prescribed to minimize hormonal fluctuations.
- Stay hydrated and practice stress-reduction techniques to help manage anxiety related to these changes.
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Follow-Up Consideration:
- Although there’s no immediate cause for alarm, if the lump does not decrease, worsens, or if you develop additional concerning symptoms (like fever, swelling, pain), consider scheduling an ultrasound to further evaluate it.
- You can also benefit from discussing the new mole with a healthcare professional if it changes in appearance or causes concern over time.
Feel assured that most lumps are benign, and it’s wise to monitor them while also taking your hormone levels into account. If you feel any further enlargements, persistent changes, or new symptoms develop, reaching out for an evaluation would be the right approach. Remember, it’s okay to seek reassurance when you feel uncertain!
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