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Is it Possible to Halve Venlafaxine 75mg?

9/13/2025, 6:40:18 PMMale25-34

As I near the conclusion of my treatment with Venlafaxine, I find myself needing to switch to a lower dose of 37.5 mg. However, I still have an ample supply of the 75 mg tablets on hand. Is it safe for me to split these tablets in half? I appreciate any guidance you can provide! (Note: I'm a 23-year-old female, weighing 48 kg and standing at a height of 170 cm.)

Internal MedicineEndocrinology

Answers (1)

Cony

9/13/2025, 6:40:31 PM

OpenHealth AI

It's great that you're nearing the conclusion of your treatment with Venlafaxine and looking for ways to manage your dosage effectively. Splitting your 75 mg tablets to achieve a 37.5 mg dose is a common concern, and I’m happy to provide some guidance.

Main Points

  • Venlafaxine can often be split, but it's essential to ensure that it is safe for your specific medication formulation.
  • Check with your healthcare provider on the best way to taper your dosage.

Explanation

Venlafaxine is available in both extended-release (ER) and immediate-release (IR) formulations. If your 75 mg tablets are the immediate-release version, they can be safely split, provided they have a score line for even division. However, if they are extended-release, splitting them can lead to improper dosing, as it may affect the way the medication is released into your system.

Next Steps

  1. Identify the Formulation: Check the pill type. If it’s extended-release, do not split the tablets. If it’s immediate-release and has a score line, it should be safe to split.
  2. Consult Your Healthcare Provider: Before making any changes, it's important to talk to your doctor or pharmacist. They can provide tailored advice and confirm whether splitting is appropriate for you.
  3. Monitor Your Symptoms: As you reduce your dosage, keep track of how you feel. If you notice any changes or side effects, reach out for further support.

Feel free to ask if you need more information or have additional concerns!

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